Evidence map›Paper›PMID 41401077›Full record

ArticleJournal of agricultural and food chemistry2025

Synthesis, Anthelmintic Activity, and Mechanism of Action of 5-Aryl-1

Alena Kadlecová, Karolina Dzedulionytė Müldür, Miroslav Peřina, Kristýna Bieleszová, Chao Zhang, Daniel Kováříček, Elora Valderas-García, Dominik Vítek, Miglė Valikonytė, Algirdas Šačkus and 10 more

Abstract read
In one paragraph

Article in Journal of agricultural and food chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Alena KadlecováDepatment of Experimental Biology, Faculty of Science, Palacký University, Šlechtitelů 27, CZ-77900 Olomouc, Czech Republic.ORCID 0000-0003-2200-3977
Karolina Dzedulionytė MüldürDepartment of Organic Chemistry, Kaunas University of Technology, Radvilėnu pl. 19, LT-50254 Kaunas, Lithuania.ORCID 0000-0001-7533-1988
Miroslav PeřinaDepatment of Experimental Biology, Faculty of Science, Palacký University, Šlechtitelů 27, CZ-77900 Olomouc, Czech Republic.ORCID 0000-0001-5861-8688
Kristýna BieleszováDepartment of Chemical Biology, Faculty of Science, Palacký University, Šlechtitelů 27, CZ-77900 Olomouc, Czech Republic.
Chao ZhangLaboratory of Growth Regulators, Institute of Experimental Botany, The Czech Academy of Sciences & Faculty of Science, Palacký University, Šlechtitelů 27, CZ-77900 Olomouc, Czech Republic.
Daniel KováříčekDepartment of Chemical Biology, Faculty of Science, Palacký University, Šlechtitelů 27, CZ-77900 Olomouc, Czech Republic.
Elora Valderas-GarcíaInstituto de Ganadería de Montaña (CSIC-Universidad de León), Departamento de Sanidad Animal, Grulleros, ES-24346 León, Spain.
Dominik VítekInstitute of Molecular and Translational Medicine, Faculty of Medicine, Palacký University, CZ-77515 Olomouc, Czech Republic.
Miglė ValikonytėDepartment of Organic Chemistry, Kaunas University of Technology, Radvilėnu pl. 19, LT-50254 Kaunas, Lithuania.
Algirdas ŠačkusDepartment of Organic Chemistry, Kaunas University of Technology, Radvilėnu pl. 19, LT-50254 Kaunas, Lithuania.
Joana SolovjovaDepartment of Organic Chemistry, Kaunas University of Technology, Radvilėnu pl. 19, LT-50254 Kaunas, Lithuania.
Vida MalinauskienėDepartment of Organic Chemistry, Kaunas University of Technology, Radvilėnu pl. 19, LT-50254 Kaunas, Lithuania.
Karel DoležalDepartment of Chemical Biology, Faculty of Science, Palacký University, Šlechtitelů 27, CZ-77900 Olomouc, Czech Republic.
Ondřej NovákLaboratory of Growth Regulators, Institute of Experimental Botany, The Czech Academy of Sciences & Faculty of Science, Palacký University, Šlechtitelů 27, CZ-77900 Olomouc, Czech Republic.
Florian M W GrundlerINRES - Molecular Phytomedicine, University Bonn, Karlrobert-Kreiten-Str. 13, D-53115 Bonn, Germany.
Peter RoyDepartment of Molecular Genetics & Department of Pharmacology & Toxicology, University of Toronto, The Donnelly Centre, Rm 1202 160 College St., ON M5S 3E1 Toronto, Canada.
Maria Martínez-ValladaresINRES - Molecular Phytomedicine, University Bonn, Karlrobert-Kreiten-Str. 13, D-53115 Bonn, Germany.
Jiří VollerDepatment of Experimental Biology, Faculty of Science, Palacký University, Šlechtitelů 27, CZ-77900 Olomouc, Czech Republic.
A Sylvia S SchlekerINRES - Molecular Phytomedicine, University Bonn, Karlrobert-Kreiten-Str. 13, D-53115 Bonn, Germany.
Asta ŽukauskaitėDepartment of Chemical Biology, Faculty of Science, Palacký University, Šlechtitelů 27, CZ-77900 Olomouc, Czech Republic.

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440
6 · The paper itself

Abstract

Parasitic nematodes are a significant concern in human and veterinary medicine as well as agriculture. In this study, we prepared twenty-seven 5-phenyl-1

Indexed as

AnthelminticsIndolesAnimalsCaenorhabditis elegansHaemonchusHumansLarvaMembrane Potential, MitochondrialMolecular StructureStructure-Activity RelationshipAnthelminticsIndolesC. elegansindolemitochondrial complex IIparasitic nematodesSDH inhibitor

Identifiers

PMID41401077
PMCPMC12766724

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.