Evidence map›Paper›PMID 41400936›Full record

ArticleInterdisciplinary cardiovascular and thoracic surgery2026

Maximizing Lung Transplant Donor Utilization: Developing a Lobar Donor Repository Guided by Chest Computed Tomography Visual Scoring.

Mengyang Liu, Liyang Xi, Caikang Luo, Xinchun Li, Chao Yang, Guilin Peng, Xin Xu

Abstract read
In one paragraph

Article in Interdisciplinary cardiovascular and thoracic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Mengyang LiuDepartment of Organ Transplantation, The First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, Guangzhou 510120, China.
Liyang XiDepartment of Organ Transplantation, The First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, Guangzhou 510120, China.
Caikang LuoDepartment of Organ Transplantation, The First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, Guangzhou 510120, China.ORCID 0000-0003-2080-712X
Xinchun LiDepartment of Radiology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510120, China.
Chao YangDepartment of Organ Transplantation, The First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, Guangzhou 510120, China.
Guilin PengDepartment of Organ Transplantation, The First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, Guangzhou 510120, China.
Xin XuDepartment of Organ Transplantation, The First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, Guangzhou 510120, China.ORCID 0000-0003-1066-6781

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study develops a visual scoring system based on chest computed tomography (CT) findings to assess donor lung function and explores its use for brain-dead donors.

methodsWe conducted a retrospective cohort study of 151 donors after brain death managed by our local Organ Procurement Organization from January 1 to June 30, 2024. A multidisciplinary team developed a chest CT evaluation protocol based on Fleischner Society guidelines. Lung lesions were scored lobe-by-lobe for statistical analysis.

resultsOf 151 potential donors, 56 (37.09%) underwent lung transplantation. Transplanted lungs had a higher proportion of blood type O, better oxygenation index, lower C-reactive protein and procalcitonin level, and lower CT scores compared to non-transplanted lungs. A higher total lung score (TLS) was strongly and negatively associated with lung utilization (OR 0.643, P < .001). ROC curve analysis indicated good discriminative ability for the TLS alone (AUC = 0.803). Our findings establish that chest CT visual scoring is a valuable univariable tool for assessing lungs from brain-dead donors. Based on the CT scoring results, the overall utilization rate of potential lung lobes reached 79.22%.

conclusionsIn the evaluation of donor lungs, a high TLS demonstrates a significant negative univariable association with lung utilization rates and exhibits good univariable diagnostic accuracy. The TLS has the potential to serve as a powerful and practical screening tool for donor lung assessment. Our findings suggest that chest CT visual scoring holds potential importance in assessing lungs from brain-dead donors and provides meaningful insights into the evaluation of donor lung lobes. However, further studies with larger sample sizes are required to explore these findings in greater depth.

Indexed as

Brain DeathDonor SelectionLungLung TransplantationTissue and Organ ProcurementTissue DonorsTomography, X-Ray ComputedAdultFemaleHumansMaleMiddle AgedPredictive Value of TestsRetrospective StudiesComputed tomographydonor lung evaluation organ utilizationlung transplantation

Identifiers

PMID41400936
PMCPMC12822768

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