ReviewClinical rheumatology2026
Hemoptysis as the initial presentation of ANCA-associated vasculitis in a patient with ulcerative colitis: a case report and literature review.
Review in Clinical rheumatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
We report a rare case of a 63-year-old man with ulcerative colitis (UC) who presented with hemoptysis and was diagnosed with anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), evidenced by positivity for both cytoplasmic-ANCA (c-ANCA) and perinuclear-ANCA (p-ANCA). Imaging and bronchoscopy supported pulmonary involvement. Glucocorticoid therapy led to rapid resolution of respiratory symptoms; however, steroid tapering triggered a UC flare requiring biologic therapy and eventual total colectomy. At the 3-year follow-up, the patient remained free of pulmonary symptoms. This case underscores the importance of considering AAV in UC patients with hemoptysis to enable early diagnosis and appropriate management.
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