Evidence map›Paper›PMID 41400848›Full record

Trial reportInternational ophthalmology2025

Challenging the routine: evaluating the need for postoperative management in blepharoplasty: a randomized controlled trial.

Tal Yahalomi, Doron Moscovici, Irena Kaplanov, Yuval Tal, Nir Stanescu, Gilad Spiegel, Avi Rubinov

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in International ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tal YahalomiDepartment of Ophthalmology, Samson Assuta Ashdod Hospital, Faculty of Health Sciences, Ben-Gurion University of the Negev, Ashdod, Israel. yatal25@gmail.com.ORCID http://orcid.org/0000-0002-6833-6198
Doron MoscoviciDepartment of Ophthalmology, Samson Assuta Ashdod Hospital, Faculty of Health Sciences, Ben-Gurion University of the Negev, Ashdod, Israel.
Irena KaplanovDepartment of Ophthalmology, Samson Assuta Ashdod Hospital, Faculty of Health Sciences, Ben-Gurion University of the Negev, Ashdod, Israel.
Yuval TalDepartment of Ophthalmology, Samson Assuta Ashdod Hospital, Faculty of Health Sciences, Ben-Gurion University of the Negev, Ashdod, Israel.
Nir StanescuDepartment of Ophthalmology, Samson Assuta Ashdod Hospital, Faculty of Health Sciences, Ben-Gurion University of the Negev, Ashdod, Israel.
Gilad SpiegelDepartment of Plastic and Reconstructive Surgery, Shaare Zedek Medical Center, Jerusalem, Israel.
Avi RubinovDepartment of Ophthalmology, Samson Assuta Ashdod Hospital, Faculty of Health Sciences, Ben-Gurion University of the Negev, Ashdod, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the clinical and aesthetic efficacy of postoperative topical treatments compared to conservative management following standard upper eyelid blepharoplasty.

methodsThis prospective, randomized controlled trial included 69 patients undergoing isolated upper eyelid blepharoplasty. Participants were randomized into three groups: (1) antibiotic-steroid ointment (Maxitrol), (2) antibiotic-only ointment (chloramphenicol), and (3) no topical treatment (control). Primary outcomes included patient satisfaction, pain, perceived swelling, and aesthetic results using the Stony Brook Scar Evaluation Scale (SBSES), assessed at one week and four months postoperatively. Adverse events and complications were also recorded.

resultsThere were no statistically significant differences among the three groups in patient-reported outcomes at either time point, including pain (p = 0.05), satisfaction (p = 0.3), or eyelid swelling (p = 0.9). Aesthetic evaluation by a blinded independent senior plastic surgeon showed no significant difference in SBSES scores between groups (p = 0.7). No adverse effects or postoperative infections were reported.

conclusionRoutine use of postoperative topical antibiotic or corticosteroid-containing ointments following standard upper eyelid blepharoplasty does not confer additional benefit in terms of patient satisfaction, symptom control, or aesthetic outcomes when compared with conservative care alone. Given the low infection risk, potential side effects, and concerns regarding antimicrobial resistance, a simplified postoperative regimen focusing on lubrication alone may be sufficient for uncomplicated cases. These findings support a more minimalist approach to postoperative management and emphasize the need for larger, multicenter trials to validate these results across broader surgical contexts.

Indexed as

Anti-Bacterial AgentsBlepharoplastyEyelidsPostoperative CareAdultAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedPatient SatisfactionPostoperative ComplicationsProspective StudiesTreatment OutcomeAnti-Bacterial AgentsBlepharoplastyLocal treatmentPostoperativeSteroids

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.