Evidence map›Paper›PMID 41400822›Full record

ReviewRadiologie (Heidelberg, Germany)2026

[Cardiac side effects of immunotherapy : Role of imaging in immuno-oncology].

Taraneh Aziz-Safaie, Lucia D Beissel, Annemarie Proff, Julian A Luetkens, Alexander Isaak

Abstract readEnglish AbstractReview
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In one paragraph

Review in Radiologie (Heidelberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Taraneh Aziz-SafaieKlinik für Diagnostische und Interventionelle Radiologie, Universitätsklinikum Bonn, Venusberg-Campus 1, 53127, Bonn, Deutschland. Taraneh.Aziz-Safaie@ukbonn.de.
Lucia D BeisselKlinik für Diagnostische und Interventionelle Radiologie, Universitätsklinikum Bonn, Venusberg-Campus 1, 53127, Bonn, Deutschland.
Annemarie ProffKlinik für Diagnostische und Interventionelle Radiologie, Universitätsklinikum Bonn, Venusberg-Campus 1, 53127, Bonn, Deutschland.
Julian A LuetkensKlinik für Diagnostische und Interventionelle Radiologie, Universitätsklinikum Bonn, Venusberg-Campus 1, 53127, Bonn, Deutschland.
Alexander IsaakKlinik für Diagnostische und Interventionelle Radiologie, Universitätsklinikum Bonn, Venusberg-Campus 1, 53127, Bonn, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImmunotherapies have become an integral part of modern oncology. Despite their therapeutic success, they are associated with cardiotoxic side effects that require early detection. Cardiac magnetic resonance imaging (CMR), as a noninvasive modality, enables precise tissue characterization of immune-mediated myocardial injury.

objectivesTo present cardiotoxic effects of immunotherapies and the role of CMR in diagnosis and risk stratification. MATERIALS AND

methodsCurrent scientific literature and clinical guidelines were reviewed regarding the incidence, pathophysiology, and imaging-based diagnosis of cardiotoxic effects related to immunotherapies.

resultsMyocarditis associated with immune checkpoint inhibitors is rare but linked to high mortality. Chimeric antigen receptor (CAR)-T-related cardiotoxicity often occurs in the context of cytokine release syndrome and can be assessed by CMR with respect to both functional and structural myocardial changes.

conclusionCMR plays a central role in the noninvasive diagnosis of immunotherapy-related cardiotoxicity and is essential for clinical decision-making and risk stratification.

Indexed as

CardiotoxicityImmune Checkpoint InhibitorsImmunotherapyMagnetic Resonance ImagingNeoplasmsHumansMyocarditisImmune Checkpoint InhibitorsCardiac magnetic resonance imagingCardiotoxicityCytokine release syndromeImmune checkpoint inhibitorsMyocarditis

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.