ArticleMolecular neurobiology2025
Atraric Acid Ameliorates Neurological Dysfunction in High-Fat Diet-Fed Mice by Activating Autophagy to Alleviate Brain Oxidative Stress and Neuroinflammation.
Article in Molecular neurobiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Molecular Signaling Pathways in Depression and Neuroinflammation: Focus on New Pathophysiological Proteins and Therapeutic Compounds.Antioxidants (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
The ability of atraric acid (AA), a lichen-derived metabolite with anti-inflammatory/antioxidant properties, to protect against obesity-associated neurological dysfunctions was investigated given the role of obesity in triggering neuroinflammation via free fatty acids. Model mice were fed a high-fat diet (HFD) for 12 weeks, and HT22 neurons were exposed to oleic acid/palmitic acid (OA/PA). A variety of experimental techniques, including CCK8, H&E staining, Nissl staining, QPCR, and behavioral tests (open field, elevated plus maze, and Morris water maze), have been used to assess cognitive/anxiety phenotypes. Molecular analyses, including ELISAs (TNF-α/IL-6/GM-CSF), biochemical assays (oxidative stress markers), immunofluorescence/Western blotting, H
Indexed as
Identifiers
41400793What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.