Evidence map›Paper›PMID 41400791›Full record

ArticleInternational urology and nephrology2026

En-bloc and non-en-bloc techniques for thulium laser enucleation of the prostate: a comparative study of surgical outcomes.

Haitian Song, Zhicun Li, Xinyan Che, Kaiyue Chen, Kunlin Yang, Chao Zuo, Qian Zhang, Kai Zhang, Yisen Meng

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in International urology and nephrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Haitian Song *Department of Urology, Peking University First Hospital, The Institute of Urology, Peking University, The National Urological Cancer Center of China, No. 8 Xishiku St., Xicheng District, Beijing, 100034, China.
Zhicun Li *Department of Urology, Peking University First Hospital, The Institute of Urology, Peking University, The National Urological Cancer Center of China, No. 8 Xishiku St., Xicheng District, Beijing, 100034, China.
Xinyan CheDepartment of Urology, Peking University First Hospital, The Institute of Urology, Peking University, The National Urological Cancer Center of China, No. 8 Xishiku St., Xicheng District, Beijing, 100034, China.
Kaiyue ChenDepartment of Urology, Peking University First Hospital, The Institute of Urology, Peking University, The National Urological Cancer Center of China, No. 8 Xishiku St., Xicheng District, Beijing, 100034, China.
Kunlin YangDepartment of Urology, Peking University First Hospital, The Institute of Urology, Peking University, The National Urological Cancer Center of China, No. 8 Xishiku St., Xicheng District, Beijing, 100034, China.
Chao ZuoDepartment of Urology, Peking University First Hospital, The Institute of Urology, Peking University, The National Urological Cancer Center of China, No. 8 Xishiku St., Xicheng District, Beijing, 100034, China.
Qian ZhangDepartment of Urology, Beijing Shijitan Hospital, Beijing, China.
Kai ZhangDepartment of Urology, Peking University First Hospital, The Institute of Urology, Peking University, The National Urological Cancer Center of China, No. 8 Xishiku St., Xicheng District, Beijing, 100034, China.
Yisen MengDepartment of Urology, Peking University First Hospital, The Institute of Urology, Peking University, The National Urological Cancer Center of China, No. 8 Xishiku St., Xicheng District, Beijing, 100034, China. mgyss@qq.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo compare surgical outcomes between the en-bloc and non-en-bloc techniques of thulium laser enucleation of the prostate (ThuLEP) in patients with different prostate volumes (PV).

methodsWe reviewed patients treated with ThuLEP for benign prostatic hyperplasia (BPH) at Peking University First Hospital from January 2020 to December 2022. Patients were categorized into en-bloc and non-en-bloc (the two-lobe and three-lobe techniques) according to enucleation techniques. Baseline characteristics, peri-operative and post-operative outcomes were evaluated. Subgroup analysis were conducted based on prostate volume (PV < 60 ml, 60 ≤ PV < 80 ml, and PV ≥ 80 ml). Propensity score matching (PSM) was used to reduce confounding.

resultsA total of 540 patients were included with 196 patients undergoing en-bloc enucleation and 344 patients undergoing non-en-bloc enucleation. The baseline characteristics between the two groups were similar. The en-bloc technique demonstrated reduced operation time (median: 59.0 vs. 78.0 min, P < 0.001) and increased operation efficiency (median: 0.84 vs. 0.63 g/min, P < 0.001) compared to the non-en-bloc techniques, with similar post-operative complication rates (6.1% vs. 4.7%, P = 0.458). Sub-group analysis based on prostate volume revealed that the en-bloc technique resulted in decreased operation time and improved operation efficiency for patients with PV > 80 ml and between 60 and 80 ml. However, no significant difference was observed between en-bloc and non-en-bloc techniques for patients with PV ≤ 60 ml.

conclusionsIn patients with PV > 60 ml, the en-bloc technique is advantageous in operation time and efficiency compared to non-en-bloc techniques. For those with PV < 60 ml, the en-bloc and non-en-bloc techniques exhibit similar operation time and efficiency.

Indexed as

Lasers, Solid-StateLaser TherapyProstatectomyProstatic HyperplasiaThuliumAgedHumansMaleMiddle AgedProstateRetrospective StudiesTreatment OutcomeThuliumBenign prostatic hyperplasiaEn-blocThree lobesThulium laser enucleation of the prostateTwo lobes

Identifiers

PMID41400791
PMCPMC13194294

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.