Evidence map›Paper›PMID 41400758›Full record

SynthesisCurrent cardiology reports2025

Outcomes of Adding Computed Tomography Angiography for Pre-procedural Planning of Left Atrial Appendage Occlusion: a Systematic Review and Meta-analysis.

Vinicius Pereira, Julia Fernandes, Rafael Petri Santos Pinheiro, Naieli Andrade, Eric Katsuyama, Chidubem Ezenna, Mrinal Murali Krishna, Meghna Joseph, Andrew M Goldsweig, Wilton F Gomes

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Current cardiology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Vinicius PereiraFacultad de Ciencias Biomédicas, Universidad Austral, Pilar, Buenos Aires, Argentina.
Julia FernandesCentro de Ensino e Pesquisa Albert Einstein, Faculdade Israelita de Ciências da Saúde Albert Einstein, São Paulo, Brazil.
Rafael Petri Santos PinheiroFaculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Naieli AndradeFaculdade de Medicina, Escola Bahiana de Medicina e Saúde Pública, Salvador, Brazil, Bahia.
Eric KatsuyamaFaculdade de Medicina do ABC, São Paulo, Brazil.
Chidubem EzennaDepartment of Medicine, University of Massachusetts - Baystate Medical Center, Springfield, MA, USA.
Mrinal Murali KrishnaInternal Medicine, Medical College Thiruvananthapuram, Mavelikara, India.
Meghna JosephMedical College Thiruvananthapuram, Thodupuzha, India.
Andrew M GoldsweigDepartment of Cardiovascular Medicine, Baystate Medical Center and Division of Cardiovascular Medicine, University of Massachusetts-Baystate, Springfield, MA, USA.
Wilton F GomesDepartment of Interventional Cardiology, INC Hospital, Universidade Federal do Paraná, Jeremias Meciel Perretto 300, Curitiba, Paraná, Brazil. wiltonfg@cardiol.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMulti-society expert consensus statements on catheter-based left atrial appendage occlusion (LAAO) suggest transesophageal echocardiography (TEE) or cardiac computed tomography angiography (CCTA) for pre-procedural planning. However, evidence comparing the outcomes of adding CCTA to TEE on procedural success is limited.

objectivePerform a systematic review and meta-analysis to determine the impact of adding CCTA to TEE for pre-procedural planning in patients undergoing LAAO.

methodsWe systematically searched Cochrane, Embase, and Medline for observational studies and randomized controlled trials (RCTs) comparing the addition of CCTA vs. TEE alone. The primary endpoint was procedural success. Risk ratios (RRs) with 95% confidence intervals (CIs) were pooled across studies using a random-effects model.

resultsSystematic review identified four studies for meta-analysis, three RCTs and one observational study, including a total of 824 patients, of whom 496 (60.2%) underwent additional CCTA. In the pooled analysis, procedural success was higher with added CCTA (RR 1.10; 95% CI 1.01-1.19; p = 0.022; I²=52%). A subgroup analysis of only RCTs confirmed these findings with a slightly higher magnitude of effect and lower heterogeneity (RR 1.15; 95% CI: 1.06-1.25; I

Indexed as

Atrial AppendageAtrial FibrillationComputed Tomography AngiographyCardiac CatheterizationEchocardiography, TransesophagealHumansPreoperative CareTreatment OutcomeAtrial fibrillationCardiac CTLeft atrial appendage occlusionTransesophageal echocardiography

Identifiers

PMID41400758

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.