Evidence map›Paper›PMID 41400746›Full record

ArticleAnalytical sciences : the international journal of the Japan Society for Analytical Chemistry2026

Enhancing peroxidase-like activity of Cu/Ag nanoclusters nanozyme by G/C-rich sequence for colorimetric determination of ochratoxin A.

Shaojie Xia, Zhenyuan Yang, Xiaohui Sun, Junjie Huang, Kuan Peng, Yonghong Wang

Abstract read
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In one paragraph

Article in Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Electrochemical analysis of miRNA for liquid biopsy.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2026
    Article
  2. Beyond ensemble averages: single-entity approaches for complex systems.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2026
    Review
  3. Magnetic nanomaterials in analytical chemistry: toward enhanced separation and detection methodologies.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shaojie XiaState Key Laboratory of Utilization of Woody Oil Resource, College of Life Sciences and Technology, Central South University of Forestry and Technology, Changsha, 410004, China.
Zhenyuan YangState Key Laboratory of Utilization of Woody Oil Resource, College of Life Sciences and Technology, Central South University of Forestry and Technology, Changsha, 410004, China.
Xiaohui SunState Key Laboratory of Utilization of Woody Oil Resource, College of Life Sciences and Technology, Central South University of Forestry and Technology, Changsha, 410004, China.
Junjie HuangState Key Laboratory of Utilization of Woody Oil Resource, College of Life Sciences and Technology, Central South University of Forestry and Technology, Changsha, 410004, China.
Kuan PengState Key Laboratory of Utilization of Woody Oil Resource, College of Life Sciences and Technology, Central South University of Forestry and Technology, Changsha, 410004, China.
Yonghong WangState Key Laboratory of Utilization of Woody Oil Resource, College of Life Sciences and Technology, Central South University of Forestry and Technology, Changsha, 410004, China. bionano@163.com.

Funding

Hunan Provincial Natural Science Foundation of China 2024JJ8264Training Program for Excellent Young Innovators of Changsha kq2106053
6 · The paper itself

Abstract

Ochratoxin A (OTA), a highly toxic mycotoxin, extensively contaminates a wide range of food commodities. Given increasing demands for sensitive and user-friendly detection platforms, we developed a colorimetric OTA biosensor leveraging copper-silver nanoclusters (Cu/Ag NCs), whose peroxidase-like activity is augmented via G/C-rich DNA hybridization. The system employs two tailored DNA strands: a template strand featuring a cytosine-rich domain for NC synthesis flanked by terminal recognition segments and an enhancer strand containing a guanine-rich signal amplification domain and a complementary linker. Upon OTA binding with the aptamer, the apt-template complex dissociates, facilitating template-enhancer hybridization to form G/C-rich double-stranded DNA. This structural transition substantially enhances the peroxidase-like activity of DNA-Cu/Ag NCs, accelerating the oxidation of 3,3',5,5'-tetramethylbenzidine by H

Indexed as

Biosensing TechniquesColorimetryCopperMetal NanoparticlesOchratoxinsPeroxidaseSilverDNALimit of DetectionCopperDNAochratoxin AOchratoxinsPeroxidaseSilverAptamerColorimetricDNA-Cu/Ag NCsOchratoxin APeroxidase-like activity

Identifiers

PMID41400746

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.