ArticlePituitary2025
The efficacy of minimally invasive intraoperative ultrasound in endoscopic pituitary surgery.
Article in Pituitary, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study aims to evaluate the clinical utility of minimally invasive intraoperative ultrasound as a real-time imaging adjunct during endoscopic endonasal pituitary adenoma surgery. The goal is to determine its effectiveness in tumor localization, identification of critical structures, and detection of residual tumor tissue.
methodsA retrospective analysis was conducted on 22 patients who underwent endoscopic endonasal pituitary surgery with intraoperative ultrasound at our institution from August 2024 to June 2025. The ultrasound probe was used before dural opening to identify the tumor, normal gland, and adjacent structures, including the internal carotid artery (ICA). After tumor resection, ultrasound was employed to assess residual tumor. Clinical and surgical outcomes, including extent of resection and perioperative complications, were reviewed.
resultsIntraoperative ultrasound enabled clear visualization of the tumor-normal gland interface in both solid and cystic macroadenomas, facilitating safe and precise resection. The technique aided in identification of the ICA during cavernous sinus invasion, reducing vascular injury risk. In cases where tumors were not visible on preoperative magnetic resonance imaging (MRI), intraoperative ultrasound successfully detected the lesions, allowing targeted resection. Gross total resection (GTR) was achieved in 86.4% of cases. The median follow-up was 8 months (range, 3-13 months). There were no new postoperative hormonal deficits. Transient diabetes insipidus occurred in three cases, and all resolved within three months.
conclusionIntraoperative ultrasound provides real-time, high-resolution imaging that enhances the precision and safety of endoscopic pituitary surgery. The technique is particularly valuable for tumor localization, identification of critical neurovascular structures, and detection of residual tumor tissue. Further studies are warranted to validate a broader applicability and refine its role in differentiating tumor from normal gland tissue.
Indexed as
Identifiers
41400717What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.