Evidence map›Paper›PMID 41400477›Full record

ArticlemBio2026

Decoding the multifaceted role of erythrocyte PMCA4b in oxidative stress-mediated malaria protection and artemisinin resistance.

Priya Agrohi, Swati Garg, Shreeja Biswas, Preeti Maurya, Vijay Kumar, Jyoti Sharma, Bidhan Goswami, Samir Kumar Sil, Mrigendra Pal Singh, Sunil Kumar Chand and 7 more

Abstract read
In one paragraph

Article in mBio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Priya Agrohi *ICMR-National Institute of Malaria Research, New Delhi, India.ORCID 0000-0001-7993-9157
Swati Garg *Special Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, India.ORCID 0000-0002-7497-2027
Shreeja BiswasSpecial Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, India.
Preeti MauryaSpecial Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, India.
Vijay KumarICMR-National Institute of Malaria Research, New Delhi, India.
Jyoti SharmaSpecial Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, India.
Bidhan GoswamiDepartment of Human Physiology, Molecular Genetics and Cancer Biology Laboratory, Tripura University, Suryamani Nagar, Tripura, India.
Samir Kumar SilDepartment of Human Physiology, Tripura University, Suryamaninagar, Tripura, India.
Mrigendra Pal SinghICMR-National Institute of Malaria Research Field Unit Jabalpur, Jabalpur, Madhya Pradesh, India.
Sunil Kumar ChandICMR-National Institute of Malaria Research Field Unit Jabalpur, Jabalpur, Madhya Pradesh, India.
Sneh ShaliniIndian Council of Medical Research, New Delhi, India.
Om P SinghICMR-National Institute of Malaria Research, New Delhi, India.ORCID 0000-0001-5135-6654
Gunanidhi DhangadamajhiDepartment of Biotechnology, North Orissa University, Baripada, Odisha, India.
Neelima MishraICMR-National Institute of Malaria Research, New Delhi, India.
Sivaprakash RamalingamCSIR-Institute of Genomics and Integrative Biology (CSIR-IGIB), New Delhi, India.
Prashant Kumar MallickICMR-National Institute of Malaria Research, New Delhi, India.ORCID 0000-0002-5866-717X
Shailja SinghSpecial Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, India.ORCID 0000-0001-5286-6605

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ATP2B4 gene, encoding the PMCA4b Ca²

Indexed as

AntimalarialsArtemisininsDrug ResistanceErythrocytesMalaria, FalciparumOxidative StressPlasma Membrane Calcium-Transporting ATPasesPlasmodium falciparumCalciumFemaleGenotypeHumansMaleAntimalarialsartemisininArtemisininsATP2B4 protein, humanCalciumPlasma Membrane Calcium-Transporting ATPasesartemisinin resistanceATP2B4malariaoxidative stressPMCA4bresveratrol

Identifiers

PMID41400477
PMCPMC12802218

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.