Evidence map›Paper›PMID 41400437›Full record

SynthesisJournal of glaucoma2026

Micropulse Cyclophotocoagulation Versus Continuous Wave Cyclophotocoagulation: A Meta-Analysis.

Johar Abbas, Ghadeer Mohammed Abbas, Muhammad Maaz, Imama Yaseen, Rabia Asim, Sameen Mukhtar, Zainab Rustam, Somaiya Ahmed, Hajira Arooj, Bo Wang

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Journal of glaucoma, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Johar AbbasDepartment of Glaucoma, Al-Shifa Trust Eye Hospital, Rawalpindi, Pakistan.
Ghadeer Mohammed AbbasUniversity of Kufa College of Medicine, Najaf, Iraq.
Muhammad MaazBacha Khan Medical College, Mardan, Pakistan.
Imama YaseenRashid Latif Medical College, Lahore, Pakistan.
Rabia AsimShaheed Mohtarma Benazir Bhutto Medical College Lyari, Karachi, Pakistan.
Sameen MukhtarDow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Zainab RustamWilmer Eye Institute, Johns Hopkins Hospital, Baltimore, MD.
Somaiya AhmedSir Salimullah Medical College, Dhaka, Bangladesh.
Hajira AroojRawalpindi Medical University, Rawalpindi, Pakistan.
Bo WangWilmer Eye Institute, Johns Hopkins Hospital, Baltimore, MD.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PRÉCIS: In this systematic review, we find that CW-CPC produces more sustained IOP lowering in children compared with MP-CPC. PURPOSE: Micropulse cyclophotocoagulation (MP-CPC) and continuous cyclophotocoagulation (CW-CPC) are both surgical interventions used to decrease intraocular pressure (IOP) in pediatric glaucoma. Recent publications have shown conflicting results regarding the effectiveness of MP-CPC compared with CW-CPC, which this systematic review and meta-analysis aims to evaluate.

methodsFrom inception through March 2025, PubMed, Embase, Scopus, Cochrane Library, and ScienceDirect were searched for studies comparing MP-CPC and CW-CPC in treating pediatric glaucoma, with IOP reported at different time intervals. A random effects model was used across all analyses.

resultsAt 12 months, CW-CPC showed a significantly greater reduction in IOP compared with MP-CPC (MD: -6.88 mm Hg, 95% CI: -9.46 to -4.30; P < 0.00001). No significant differences in IOP lowering were observed at 1, 3, and 6 months. Overall, CW-CPC was superior in reducing IOP (MD: -4.23 mm Hg, 95% CI: -6.51 to -1.95; P = 0.0003; I² = 80%) at the last follow-up.

conclusionCW-CPC shows a significantly greater reduction in IOP than MP-CPC, particularly at long-term follow-up. These findings highlight the sustained efficacy of CW-CPC compared with MP-CPC in the management of pediatric glaucoma.

Indexed as

Ciliary BodyGlaucomaIntraocular PressureLaser CoagulationChildHumanscontinuous cyclophotocoagulationintraocular pressuremicropulse cyclophotocoagulationpediatric glaucoma

Identifiers

PMID41400437
PMCPMC13015805

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.