Evidence map›Paper›PMID 41400398›Full record

ArticleMicrobiology spectrum2026

Tamoxifen inhibits histidine kinases of

Abhishek Garg, Devendra Pratap Singh, Mansi Pandit, Vandana Malhotra, Deepak Kumar Saini

Abstract read
In one paragraph

Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Abhishek GargDepartment of Biochemistry, University of Delhi South Campus, New Delhi, India.ORCID 0000-0002-3436-2531
Devendra Pratap SinghDepartment of Developmental Biology and Genetics, Indian Institute of Science, Bengaluru, Karnataka, India.
Mansi PanditBioinformatics Infrastructure Facility, Sri Venkateswara College, University of Delhi, New Delhi, India.
Vandana MalhotraDepartment of Biochemistry, Sri Venkateswara College, University of Delhi, New Delhi, India.ORCID 0000-0001-6138-1909
Deepak Kumar SainiDepartment of Developmental Biology and Genetics, Indian Institute of Science, Bengaluru, Karnataka, India.ORCID 0000-0001-6671-7256

Funding

BIRAC, DBT BIRAC/PMU/2019/Sentinels-001Department of Biotechnology, Ministry of Science and Technology, India BT/PR31937/MED/29/1404/2019Department of Biotechnology, Ministry of Science and Technology, India BT/PR41993/MED/29/1559/2021
6 · The paper itself

Abstract

Two-component signaling systems (TCSSs) serve as primary signal transduction pathways in bacteria, regulating essential processes including growth, physiology, and virulence, making them attractive drug targets. In

Indexed as

Bacterial ProteinsHistidine KinaseMycobacterium tuberculosisSignal TransductionTamoxifenGene Expression Regulation, BacterialMolecular Docking SimulationMycobacterium bovisPhosphorylationBacterial ProteinsHistidine KinasePhoR protein, BacteriaTamoxifenanti-TB drug targethistidine kinaseM. tuberculosisPhoR and MtrBsmall-molecule inhibitorstamoxifentwo-component signaling system

Identifiers

PMID41400398
PMCPMC12889096

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.