ReviewChinese herbal medicines2025
Natural compounds from traditional Chinese medicine regulating stem cell fate: Identification and therapeutic potential.
Review in Chinese herbal medicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Natural product therapy in diabetic kidney disease: emerging multiomics-mediated signalling pathway and molecular target.Chinese medicine · 2026Review
- Enhancing islet transplantation outcomes in T1DM: The promise of mesenchymal stem cells and exosomes.International journal of pharmaceutics: X · 2026Review
- Article
- 14-Deoxy-11,12-didehydroandrographolide Promotes Ex Vivo Expansion of Umbilical Cord Blood Stem Cells through Stemness-Related Gene Regulation.ACS omega · 2026Article
- Challenges of regenerative medicine: New strategies from traditional Chinese medicine.Chinese herbal medicines · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The problems of uncontrolled stem cell differentiation and the limited number of cells available represent significant obstacles to the advancement of stem cell research in the medical field. It is therefore imperative to control the potential of stem cells and to develop effective methods to regulate stem cell fate. A number of natural products derived from TCM have been shown to provide valuable insights into the regulation of biological signals and epigenetic mechanisms in stem cells. Furthermore, the structural modification of these natural products by synthetic means promises to unlock a wealth of possibilities in the field of precision regenerative medicine. However, a systematic and comprehensive review of these natural products has yet to be conducted. This article presents an overview of the natural products that have been identified as regulating the fate of stem cells. It includes a discussion of the classification, mechanism of action, and current prospects for the application of these natural products as lead compounds. This provides valuable insights for the advancement of TCM modernization and internationalization, precision regenerative medicine involving natural products and stem cells, the discovery of green lead compounds, and the development of new drugs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.