Evidence map›Paper›PMID 41399783›Full record

ArticleChinese herbal medicines2025

Target deconvolution strategies in TCM: Bridging medicinal properties with therapeutic efficacies.

Yuanyuan Hou, Min Jiang, Gang Bai

Abstract read
In one paragraph

Article in Chinese herbal medicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yuanyuan HouCollege of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300350, China.
Min JiangCollege of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300350, China.
Gang BaiCollege of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300350, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The discovery and characterization of molecular targets from traditional Chinese medicine (TCM) represents a paradigm shift in contemporary drug development. This approach systematically bridges empirical TCM knowledge with modern pharmacological principles, establishing a robust framework for rational drug design. Through integrative systems-chemical biology approaches, we can now mechanistically elucidate the therapeutic basis of TCM's bioactive properties, facilitating the accelerated identification of both novel molecular targets and conserved pharmacological pathways. This multidisciplinary strategy significantly enhances drug development efficiency while advancing therapeutic innovation to address critical unmet medical needs. With the rapid advancement of next-generation target deconvolution technologies and AI-driven computational platforms, TCM is poised to make increasingly substantial contributions to modern pharmacotherapy.

Indexed as

chemical biologymedicinal propertiessystems biologytarget deconvolutiontherapeutic efficacies

Identifiers

PMID41399783
PMCPMC12702422

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.