Evidence map›Paper›PMID 41399632›Full record

ArticleBioinformatics advances2025

Bridging worlds: connecting glycan representations with glycoinformatics via Universal Input and a canonicalized nomenclature.

James Urban, Roman Joeres, Daniel Bojar

Abstract read
In one paragraph

Article in Bioinformatics advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

James UrbanDepartment of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg 40530, Sweden.
Roman JoeresDepartment of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg 40530, Sweden.
Daniel BojarDepartment of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg 40530, Sweden.ORCID https://orcid.org/0000-0002-3008-7851

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Motivation: As the field of glycobiology has developed, so too have different glycan nomenclature systems. While each system serves specific purposes, this multiplicity creates challenges for usability, data integration, and knowledge sharing across different databases and computational tools. Results: We present a practical framework for automated nomenclature conversion that takes any glycan nomenclature as input without requiring declaration of the specific language and outputs a canonicalized IUPAC-condensed format as a standardized representation. Our implementation handles all common nomenclatures including WURCS, GlycoCT, IUPAC-condensed/extended, GLYCAM, CSDB-linear, LinearCode, GlycoWorkbench, GlySeeker, Oxford, and KCF, along with common typos, and manages complex cases including structural ambiguities, modifications, uncertainty in linkage information, and different compositional representations. This Universal Input framework can translate more than 10 nomenclatures in <1 ms per glycan, tested on over 150 000 sequences with 98%-100% coverage, enabling seamless integration of existing glycan databases and tools while maintaining the specific advantages of each representation system. Availability and implementation: Universal Input is implemented within the glycowork Python package, available at https://github.com/BojarLab/glycowork and our web app https://canonicalize.streamlit.app/.

Identifiers

PMID41399632
PMCPMC12702141

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.