Evidence map›Paper›PMID 41399610›Full record

ArticleRespiratory medicine case reports2025

Cytotoxicity and virulence attributes of

T C Bolig, S H Nozick, C M R Axline, I Niki, A Valdes, A Alisoltanidehkordi, T L Turner, F P F Campos, H Namkoong, P Riviere and 4 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Respiratory medicine case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

T C BoligDepartment of Medicine, Division of Pulmonary and Critical Care, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
S H NozickDepartment of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
C M R AxlineDepartment of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
I NikiDepartment of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
A ValdesDepartment of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
A AlisoltanidehkordiDepartment of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
T L TurnerDepartment of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
F P F CamposDivisão de Clinica Médica, Hospital Universitário, Universidade de São Paulo, São Paulo, Brazil.
H NamkoongDepartment of Pulmonary Medicine, Eiju General Hospital, Tokyo, Japan.
P RiviereHôpital Duchenne, Infectious Disease Department, Boulogne-sur-Mer, France.
J RelloCentro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto Salud Carlos, Madrid, Spain.
E OzerCenter for Pathogen Genomics and Microbial Evolution, Robert J. Havey Institute for Global Health, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
R WunderinkDepartment of Medicine, Division of Pulmonary and Critical Care, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
A R HauserDepartment of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

Funding

Population Analysis of Pseudomonas aeruginosa VirulenceR01AI118257 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI HAUSER, ALAN R · 2016 to 2025
$4.9M
Biomarkers for Highly Virulent Pseudomonas aeruginosa StrainsR21AI129167 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI HAUSER, ALAN R · 2017 to 2018
$570k
Dynamics of Pseudomonas aeruginosa During BacteremiaR21AI153953 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI HAUSER, ALAN R · 2020 to 2021
$435k
NIAID NIH HHS R01 AI118257NIAID NIH HHS R21 AI129167NIAID NIH HHS R21 AI153953
6 · The paper itself

Abstract

Background: Methods: To assess whether some strains of Results: The NP isolates did not share a single lineage or sequence type. There was no significant difference in cytotoxicity or Conclusions: Future studies of NP should focus on larger numbers of patients and bacterial strains to further explore whether NP isolates have enhanced cytotoxicity, examine a broader range of bacterial phenotypes and virulence determinants, and consider the role of host factors.

Indexed as

Case reportCytotoxicityGalleriaPseudomonas aeruginosa, necrotizing pneumoniaVirulence

Identifiers

PMID41399610
PMCPMC12702255

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.