Evidence map›Paper›PMID 41399516›Full record

ArticleiScience2025

Underlying mechanisms of visual mismatch responses - An EEG-fMRI study.

Insa Schlossmacher, Ina Protmann, Jacky Dilly, David Hofmann, Torge Dellert, Antje Peters, Marie-Luise Roth-Paysen, Robert Moeck, Maximilian Bruchmann, Thomas Straube

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Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Insa SchlossmacherInstitute of Medical Psychology and Systems Neuroscience, University of Münster, 48149 Münster, Germany.
Ina ProtmannInstitute of Medical Psychology and Systems Neuroscience, University of Münster, 48149 Münster, Germany.
Jacky DillyInstitute of Medical Psychology and Systems Neuroscience, University of Münster, 48149 Münster, Germany.
David HofmannInstitute of Medical Psychology and Systems Neuroscience, University of Münster, 48149 Münster, Germany.
Torge DellertInstitute of Medical Psychology and Systems Neuroscience, University of Münster, 48149 Münster, Germany.
Antje PetersInstitute of Medical Psychology and Systems Neuroscience, University of Münster, 48149 Münster, Germany.
Marie-Luise Roth-PaysenInstitute of Medical Psychology and Systems Neuroscience, University of Münster, 48149 Münster, Germany.
Robert MoeckInstitute of Medical Psychology and Systems Neuroscience, University of Münster, 48149 Münster, Germany.
Maximilian BruchmannInstitute of Medical Psychology and Systems Neuroscience, University of Münster, 48149 Münster, Germany.
Thomas StraubeInstitute of Medical Psychology and Systems Neuroscience, University of Münster, 48149 Münster, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Unexpected compared to expected visual events are accompanied by stronger neural responses. Two key mechanisms for these heightened responses are prediction errors to oddballs and adaptation to frequent stimuli. Whether these mechanisms vary systematically between early and late responses or differentlt in different cortical areas is yet unknown. In the current study, we simultaneously measured EEG and fMRI during an oddball task with control conditions tailored to distinguish between the different mechanisms. Results showed visual mismatch negativity and an enhanced P3 in the EEG and increased activations in the occipital cortex (OC) and superior parietal lobe (SPL) in fMRI. While adaptation predominantly drove early mismatch responses in the EEG and posterior OC, responses at later time points and in the anterior OC and SPL could best be explained by prediction error. This pattern suggests that the relative contribution of different mechanisms to deviance processing varies systematically in time and space.

Indexed as

Cognitive neuroscienceNeuroscienceSensory neuroscience

Identifiers

PMID41399516
PMCPMC12702045

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.