Evidence map›Paper›PMID 41399486›Full record

ArticleJournal of pharmaceutical analysis2025

Real-time monitoring and

Keyun Zeng, Fang Fan, Yuqi Tang, Xiaoyu Wang, Diya Lv, Jieman Lin, Yuxin Zhang, Yingying Zhu, Yifeng Chai, Xiaofei Chen and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of pharmaceutical analysis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Keyun ZengSchool of Pharmacy, Naval Medical University (Second Military Medical University) and Shanghai Key Laboratory for Pharmaceutical Metabolite Research, Shanghai, 200433, China.
Fang FanSchool of Pharmacy, Naval Medical University (Second Military Medical University) and Shanghai Key Laboratory for Pharmaceutical Metabolite Research, Shanghai, 200433, China.
Yuqi TangInstitute of Advanced Materials and School of Chemistry and Chemical Engineering, Southeast University, Nanjing, 211189, China.
Xiaoyu WangDepartment of Clinical Pharmacy, The General Hospital of Western Theater Command, Chengdu, 610000, China.
Diya LvSchool of Pharmacy, Naval Medical University (Second Military Medical University) and Shanghai Key Laboratory for Pharmaceutical Metabolite Research, Shanghai, 200433, China.
Jieman LinSchool of Pharmacy, Naval Medical University (Second Military Medical University) and Shanghai Key Laboratory for Pharmaceutical Metabolite Research, Shanghai, 200433, China.
Yuxin ZhangSchool of Pharmacy, Naval Medical University (Second Military Medical University) and Shanghai Key Laboratory for Pharmaceutical Metabolite Research, Shanghai, 200433, China.
Yingying ZhuSchool of Pharmacy, Naval Medical University (Second Military Medical University) and Shanghai Key Laboratory for Pharmaceutical Metabolite Research, Shanghai, 200433, China.
Yifeng ChaiSchool of Pharmacy, Naval Medical University (Second Military Medical University) and Shanghai Key Laboratory for Pharmaceutical Metabolite Research, Shanghai, 200433, China.
Xiaofei ChenSchool of Pharmacy, Naval Medical University (Second Military Medical University) and Shanghai Key Laboratory for Pharmaceutical Metabolite Research, Shanghai, 200433, China.
Quan LiInstitute of Advanced Materials and School of Chemistry and Chemical Engineering, Southeast University, Nanjing, 211189, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acetylcholinesterase (AChE) plays a crucial role in the activities of the nervous system, and its abnormal function can lead to the occurrence and development of neurodegenerative diseases. Hence, an effective method for real-time monitoring of AChE activity is essential. Very recently, several fluorescence sensors have been developed for the detection of AChE activity, but they are usually imaging in the visible region, relatively small Stokes shifts, or long response times, limiting their application for real-time monitoring

Indexed as

Acetylcholinesterase (AChE)In vivo visualizationNear-infrared (NIR) fluorescent probeReal-time monitoring

Identifiers

PMID41399486
PMCPMC12702430

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.