Evidence map›Paper›PMID 41399481›Full record

ArticleBrain & spine2025

Nerve transfers improve upper limb function in children with acute flaccid myelitis.

Marga Serafimova, Justus L Groen, Martijn Ja Malessy, Willem Pondaag

Abstract read
In one paragraph

Article in Brain & spine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marga SerafimovaDepartment of Neurosurgery, Leiden NerveCenter, Leiden University Medical Center, the Netherlands.
Justus L GroenDepartment of Neurosurgery, Leiden NerveCenter, Leiden University Medical Center, the Netherlands.
Martijn Ja MalessyDepartment of Neurosurgery, Leiden NerveCenter, Leiden University Medical Center, the Netherlands.
Willem PondaagDepartment of Neurosurgery, Leiden NerveCenter, Leiden University Medical Center, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Acute flaccid myelitis (AFM) is a rare disease affecting the spinal cord resulting in flaccid weakness that may involve any limb and can lead to significant long-term sequalae. Methods: Collected were results on children affected with AFM who were treated with nerve transfer surgery between 2016 and 2024 in a tertiary referral centre. Results: Eight children underwent 13 upper limb nerve transfers. Surgery was performed on average 15 months after disease onset. The average follow-up time was 27 months. All but one child showed improvement in upper limb function following surgical intervention. Procedures directed at elbow function deficits had better functional outcome compared to nerve transfers for shoulder function. Discussion and conclusion: Standard nerve transfers used for brachial plexus injuries were often not possible in these children due to donor nerve deficits. Alternative and less utilized transfers are discussed. We concluded that selected nerve transfers are a reliable method to restore function in children with AFM.

Indexed as

Acute flaccid myelitisBrachial plexusCentral Nervous System Viral Diseases / surgery∗ [MESH]Child[MESH]Nerve Transfer / methods∗[MESH]

Identifiers

PMID41399481
PMCPMC12702061

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.