Evidence map›Paper›PMID 41399472›Full record

ArticleEClinicalMedicine2025

Efficacy of a school-based, universal prevention programme for depression and anxiety in adolescents (OurFutures Mental Health): a two-arm cluster-randomised controlled trial.

Lucinda Grummitt, Siobhan O'Dean, Louise Birrell, Sasha Bailey, Isobel Ivison, Emily Hunter, An Nguyen, Erin Veronica Kelly, Lauren A Gardner, Katrina E Champion and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EClinicalMedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Lucinda GrummittThe Matilda Centre for Research in Mental Health and Substance Use, The University of Sydney, Sydney, NSW, Australia.
Siobhan O'DeanThe Matilda Centre for Research in Mental Health and Substance Use, The University of Sydney, Sydney, NSW, Australia.
Louise BirrellThe Matilda Centre for Research in Mental Health and Substance Use, The University of Sydney, Sydney, NSW, Australia.
Sasha BaileyThe Matilda Centre for Research in Mental Health and Substance Use, The University of Sydney, Sydney, NSW, Australia.
Isobel IvisonThe Matilda Centre for Research in Mental Health and Substance Use, The University of Sydney, Sydney, NSW, Australia.
Emily HunterThe Matilda Centre for Research in Mental Health and Substance Use, The University of Sydney, Sydney, NSW, Australia.
An NguyenThe Matilda Centre for Research in Mental Health and Substance Use, The University of Sydney, Sydney, NSW, Australia.
Erin Veronica KellyThe Matilda Centre for Research in Mental Health and Substance Use, The University of Sydney, Sydney, NSW, Australia.
Lauren A GardnerThe Matilda Centre for Research in Mental Health and Substance Use, The University of Sydney, Sydney, NSW, Australia.
Katrina E ChampionThe Matilda Centre for Research in Mental Health and Substance Use, The University of Sydney, Sydney, NSW, Australia.
Cath ChapmanThe Matilda Centre for Research in Mental Health and Substance Use, The University of Sydney, Sydney, NSW, Australia.
Maree TeessonThe Matilda Centre for Research in Mental Health and Substance Use, The University of Sydney, Sydney, NSW, Australia.
Nicola C NewtonThe Matilda Centre for Research in Mental Health and Substance Use, The University of Sydney, Sydney, NSW, Australia.
Emma L BarrettThe Matilda Centre for Research in Mental Health and Substance Use, The University of Sydney, Sydney, NSW, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Adolescence is a critical period for the onset of mental health challenges. We evaluated the efficacy of a school-based intervention ( Methods: A two-arm cluster-randomised controlled trial was conducted from 2023 to 2024 with Year 8/9 students from 10 secondary schools in Australia. Schools were randomised (1:1) to the Findings: Between Dec 6, 2022 and April 12, 2024, we recruited 17 schools (1785 students), of which 10 schools (784 students) participated in the baseline assessment (mean age = 13.8 years; 467 [59.6%] male; intervention: 6 schools, 497 students; control: 4 schools, 287 students). Seven schools withdrew prior to baseline (6 control; 1 intervention). Knowledge scores were significantly higher in the intervention group post-intervention, but not at 3 months (β = 0.30, 95% CI: -0.32-0.91, p = 0.34). No significant intervention effects were observed for depressive symptoms at 3-months (β = -0.94, 95% CI: -1.88 to 0.04, p = 0.055). However, the intervention group showed a greater reduction in anxiety symptoms at 3-month follow-up compared to active control (β = -1.05, 95% CI: -1.93 to -0.12, p = 0.024). No adverse events were reported. Interpretation: Funding: Paul Ramsay Foundation.

Indexed as

Mental healthPreventionRandomised controlled trialSchool

Identifiers

PMID41399472
PMCPMC12702296

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.