Evidence map›Paper›PMID 41399409›Full record

ArticleJournal of pharmaceutical analysis2025

Revolutionizing antibiotic therapy: Polymyxin B and Fe

Xiangrong Wei, Xinhui Cao, Chengyi Xu, Guangwei Shi, Hong Wang, Jinming Liu, Huiyang Li, Bingmei Yao, Yudong Zhang, Liqun Jiang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of pharmaceutical analysis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xiangrong WeiXuzhou Medical University, Xuzhou, Jiangsu, 211009, China.
Xinhui CaoXuzhou Medical University, Xuzhou, Jiangsu, 211009, China.
Chengyi XuXuzhou Medical University, Xuzhou, Jiangsu, 211009, China.
Guangwei ShiXuzhou Medical University, Xuzhou, Jiangsu, 211009, China.
Hong WangXuzhou Medical University, Xuzhou, Jiangsu, 211009, China.
Jinming LiuXuzhou Medical University, Xuzhou, Jiangsu, 211009, China.
Huiyang LiXuzhou Medical University, Xuzhou, Jiangsu, 211009, China.
Bingmei YaoXuzhou Medical University, Xuzhou, Jiangsu, 211009, China.
Yudong ZhangXuzhou Medical University, Xuzhou, Jiangsu, 211009, China.
Liqun JiangXuzhou Medical University, Xuzhou, Jiangsu, 211009, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To address the pressing issue of bacterial resistance, antibiotics with new mechanisms were urgently needed; yet, the majority of efforts centered on discovering novel structural compounds, often plagued by lengthy research timelines and unpredictability. In this study, we introduce an alternative strategy that rejuvenates outdated antibiotics through a unique delivery system. Specifically, we leveraged polymyxin B (PMB) and created a liposomal carrier encapsulating PMB and Fe

Indexed as

Acinetobacter baumanniiDrug deliveryDrug-resistant bacteriaFerroptosisPolymyxin B

Identifiers

PMID41399409
PMCPMC12702001

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.