Evidence map›Paper›PMID 41399356›Full record

ArticleMaterials today. Bio2025

Metal polyphenol CA-V nanozymes promote acute wound healing by destroying the ROS-inflammation cascade cycle.

Liuqin Huang, Xinyu Zhao, Shuo Zhang, Yan Xu, Haibai Wei, Meng Zhang, Huimin Feng, Xianwen Wang, Yang Zheng, Xiaoliang Zheng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Liuqin HuangLiuzhou Hospital, Guangzhou Women and Children's Medical Center, Liuzhou, 545616, China.
Xinyu ZhaoDepartment of Burns, The First Affiliated Hospital of Anhui Medical University, Hefei, 230032, China.
Shuo ZhangDepartment of Burns, The First Affiliated Hospital of Anhui Medical University, Hefei, 230032, China.
Yan XuLiuzhou Hospital, Guangzhou Women and Children's Medical Center, Liuzhou, 545616, China.
Haibai WeiLiuzhou Hospital, Guangzhou Women and Children's Medical Center, Liuzhou, 545616, China.
Meng ZhangDepartment of Plastic Surgery, The Second Affiliated Hospital of Guangxi Medical University, Nanning, 530000, China.
Huimin FengSchool of Biomedical Engineering, Anhui Medical University, Hefei, 230032, China.
Xianwen WangSchool of Biomedical Engineering, Anhui Medical University, Hefei, 230032, China.
Yang ZhengDepartment of Plastic Surgery, The Second Affiliated Hospital of Guangxi Medical University, Nanning, 530000, China.
Xiaoliang ZhengSchool of Laboratory Medicine and Bioengineering, Hangzhou Medical College, Hangzhou, 310053, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skin ulceration impairs barrier function, and high concentrations of reactive oxygen species (ROS) and inflammatory factors in the wound microenvironment significantly delay the healing process. The effects of current clinical treatment schemes are limited, and a new strategy with both economic benefits and remarkable curative effects is urgently needed. Therefore, we constructed a metal polyphenol nanozyme with multienzyme activity aimed at targeting the key vicious cycle of ROS-induced inflammation and accelerating the early healing of wounds. First, caffeic acid and NH

Indexed as

EpithelializationInflammatory factorsMetal polyphenol nanozymeReactive oxygen speciesWounds

Identifiers

PMID41399356
PMCPMC12702350

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.