ArticleGastro hep advances2025
Geographic Differences in the Quality of Life Associated With Chronic Pancreatitis: An International, Multicenter Study.
Article in Gastro hep advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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9 authors.
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Abstract
Background and Aims: Chronic pancreatitis (CP) is a disease that is present in multiple different geographic populations and is treated similarly around the world. No study has directly compared geographic differences in clinical characteristics of CP populations from Western and other regions, nor quality of life experiences. Methods: This cross-sectional, multicenter study of adults (≥18 years) with definite CP recruited subjects at 4 centers from the Pancreatic Pain Consortium. Demographics, clinical and disease characteristics, and patient-reported outcomes, including Hospital Anxiety and Depression Scale and European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire Core 30 scores were obtained. Due to similarities in population characteristics, European and United States subjects were grouped together into a Western population. Results: A total of 528 subjects were included (Indian n = 254, Western n = 274). Compared to the Indian cohort, the Western cohort had higher mean age at enrollment (54.5 ± 13.5 v 35.9 ± 11.8 years), older age distribution, higher rates of current alcohol use (34% v 2%) and alcohol etiology of CP (53% v 17%), more constant pain (50% v 20%), higher prevalence of exocrine pancreatic insufficiency (66% v 44%), and higher rates of endoscopic treatment (61% v 43%) (all Conclusion: There appear to be demographic, etiological, and quality of life differences in the experience of CP across different populations. Reasons for these differences, including potential cultural and societal forces, need to be further explored.
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