ArticleBeijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences2025
[Rheumatoid arthritis complicated with necrotizing fasciitis: A case report].
Article in Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
This case report describes the diagnostic and therapeutic management of a 70-year-old female patient with rheumatoid arthritis (RA) complicated by necrotizing fasciitis (NF).The patient has a history of RA for over 20 years, without previous standardized diagnosis or treatment.On October 3, 2023, the patient presented with swelling and pain in the bilateral proximal interphalangeal joints, the third metacarpophalangeal joint of the right hand, bilateral wrists, knees, and ankles, accompanied by redness, swelling, pain, and fever in the left gluteal region, perianal area, perineum, and the lateral upper segment of the right thigh. Laboratory tests revealed significantly elevated levels of rheumatoid factor, anti-cyclic citrullinated peptide antibodies, white blood cells, neutrophils, C-reactive protein, and erythrocyte sedimentation rate. CT imaging showed multiple large patchy areas of increased density with blurred margins in the subcutaneous adipose tissue of the bilateral gluteal regions and lower limbs, gluteus maximus muscles, and perineum, along with exudative changes in the subcutaneous adipose tissue of the bilateral lower limbs. Surgical exploration revealed extensive black necrotic tissue, and postoperative pathological examination indicated suppurative changes with abscess formation and inflammatory necrotic tissue, accompanied by local granulation tissue hyperplasia. Bacterial culture identified
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41399087PMC12711425What OpenQuestion holds
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