ArticleBeijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences2025
[Diagnostic value of fecal calprotectin detection in infants with milk protein-allergic enteritis].
Article in Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveTo explore the diagnostic significance of fecal calprotectin detection in infants with milk protein-allergic enteritis, and to provide valuable clinical basis for the early diagnosis and treatment decision-making of infants with milk protein-allergic enteritis.
methodsA retrospective analysis was conducted on the clinical data of 87 infants with suspected milk protein-allergic enteritis admitted in Hangzhou Children's Hospital from January 2020 to January 2023, and 38 infants with confirmed milk protein-allergic enteritis were assigned to group A, 49 infants with non-milk protein-allergic enteritis were assigned to group B, and 73 healthy infants who underwent physical examinations in Hangzhou Children's Hospital during the same period were assigned to the group C. General data of the three groups were collected through questionnaires, and fecal specimens were collected to detect the level of fecal calprotectin. The area under receiver operating characteristic (ROC)curve (AUC)was used to analyze the diagnostic value of fecal calprotectin for allergic enteritis and milk protein-allergic enteritis. The correlation between eosinophilic granulocytes (EOS)and platelets (PLT)levels and fecal calprotectin levels was analyzed by Pearson method.
resultsThe levels of EOS in groups A, B and C were (0.73±0.21)×10
conclusionFecal calprotectin may have high clinical significance in infants with milk protein-allergic enteritis, and EOS and PLT levels may be positively correlated with the levels of fecal calprotectin. The higher the fecal calprotectin level, the more serious the inflammatory response.
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