Evidence map›Paper›PMID 41398963›Full record

ArticleGlobal health research and policy2025

Strengthening access to zinc and oral rehydration solution for childhood diarrheal treatment in Africa.

Nsikakabasi Samuel George, Sandra Salomy Phiri, Deborah Oluwaseun Shomuyiwa, Martha Mwaba, Francis Ima Imoke, Isack Hokelai Kaniki, Grace Mmesomachukwu Oji, Lucky Iseghehi

Abstract read
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Article in Global health research and policy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nsikakabasi Samuel GeorgeSchool of Medicine and Population Health, The University of Sheffield, Sheffield, UK.
Sandra Salomy PhiriYouth On Board Organization (YOBO), Lilongwe, Malawi. sandrasalomy.phiri@gmail.com.ORCID http://orcid.org/0000-0002-7362-2164
Deborah Oluwaseun ShomuyiwaFaculty of Pharmacy, University of Lagos, Lagos, Nigeria.
Martha MwabaMinistry of Health, Lusaka, Zambia.
Francis Ima ImokeDepartment of Public Health, University of Calabar, Calabar, Nigeria.
Isack Hokelai KanikiDodoma Regional Referral Hospital, Dodoma, Tanzania.
Grace Mmesomachukwu OjiDodoma Regional Referral Hospital, Dodoma, Tanzania.
Lucky IseghehieHealth Africa, Kano State, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Childhood diarrhea remains a formidable public health challenge in Africa, exacerbated by limited access to clean water, poor sanitation, and inadequate healthcare infrastructure, impacting millions of children annually. In sub-Saharan Africa, diarrhea ranks as the leading cause of death among children under five, representing 9% of all deaths in this age group. Zinc supplementation and oral rehydration solution have emerged as pivotal treatments for childhood diarrhea, addressing electrolyte imbalances, dehydration, reducing the severity and duration of diarrhea episodes, while rehydrating children by replacing lost fluids and electrolytes. However, there are several challenges in accessing these essential components, including limited availability, affordability, supply chain challenges, and lack of awareness. In this article, we explored the burden of diarrheal diseases, the impact of zinc and oral rehydration solution, and highlight the urgent need to prioritize and strengthen access to these interventions to significantly improve treatment outcomes and reduce the burden of childhood disease in Africa. Through implementing key strategies such as addressing affordability of these commodities, training and capacity building and supply chain strengthening, community engagement, and monitoring and evaluation, significant progress can be made in overcoming barriers and improving health outcomes for children. These will ultimately contribute to the reduction of childhood mortality and the attainment of global health goals in Africa.

Indexed as

DiarrheaFluid TherapyZincAfricaChildCost of IllnessHumansZincChild healthDiarrhea treatmentHealth promotionHealth systemsHealth systems strengthening

Identifiers

PMID41398963
PMCPMC12703901

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.