Evidence map›Paper›PMID 41398850›Full record

ArticleMedicine2025

Oblique lumbar interbody fusion combined with anterolateral screw fixation for treating severe lumbar spinal stenosis: Case series.

Xingrui Peng, Tianhang Xie, Xiandi Wang, Long Zhao, Xingxiao Pu, Xiao Hu, Xu Han, Liyu Ran, Jiancheng Zeng

Abstract read
In one paragraph

Article in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Xingrui PengDepartment of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, Sichuan, China.ORCID 0009-0007-8367-3217
Tianhang Xie
Xiandi Wang
Long Zhao
Xingxiao Pu
Xiao Hu
Xu Han
Liyu Ran

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is controversial for indirect decompression like oblique lumbar interbody fusion (OLIF) for treating severe lumbar spinal stenosis (SLSS). OLIF combined with anterolateral screw fixation (AF) can achieve decompression and fixation by single incision, which is minimally invasive. In this study, we aimed to evaluate the effectiveness and safety of OLIF-AF for treating SLSS. A retrospective study which comprised patients diagnosed with L4-5 SLSS of Schizas grade C or D caused by degenerative conditions who underwent L4-5 OLIF-AF with a follow-up of 24 months. Preoperative Visual Analog Scale score of low-back pain and leg pain, and Oswestry Disability Index, disc height, foraminal area, ligamentum flavum thickness, difference of left and right facet angle, and cross-sectional area (CSA) were compared to their 1 day, 3 months, 12 months, and 24 months postoperative counterparts. Eighty-two patients of L4-5 SLSS underwent OLIF-AF were included in this retrospective study. Ligamentum flavum thickness thinned from 4.94 ± 1.20 mm to 4.20 ± 0.95 mm after the operation, and 3.91 ± 0.78 mm and 3.87 ± 0.75 mm (all P < .05) at 12 and 24 months postoperatively. CSA expanded from 52.44 ± 15.38 mm2 to 103.98 ± 20.44 mm2 on postoperative day 1, and expand to 115.77 ± 20.04 mm2 and 117.71 ± 20.83 mm2 (all P < .05) at each annual follow-up. Visual Analog Scale score of low-back pain improved from 6.40 ± 0.99 to 2.56 ± 0.85 at 3 months postoperatively, then reached 1.55 ± 0.69 and 1.12 ± 0.64 (all P < .05) at each annual follow-up. Visual Analog Scale score of leg pain gradually improved from 6.16 ± 1.25 to 2.37 ± 0.82, 1.36 ± 0.71, and 1.10 ± 0.69 (all P < .05) at each time point. Oswestry Disability Index increased from 37.54 ± 6.01 to 18.81 ± 4.38 (P < .05) after surgery. And recovered to 12.42 ± 2.44 (P < .05) and 10.58 ± 1.63 (P < .05) at 1 and 2 years postoperatively. OLIF-AF can effectively restore disc height, foraminal area, and CSA, reducing lumbar rotation, thinning the hypertrophic ligamentum flavum, significantly improving patients' pain and function, and maintaining efficacy, indicating that OLIF-AF may be a safe and effective treatment for SLSS.

Indexed as

Bone ScrewsLumbar VertebraeSpinal FusionSpinal StenosisAgedDecompression, SurgicalFemaleHumansMaleMiddle AgedPain MeasurementRetrospective StudiesTreatment Outcomeanterolateral screw fixationindirect decompressionminimally invasiveOblique lumbar interbody fusionsevere lumbar spinal stenosis

Identifiers

PMID41398850
PMCPMC12708150

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.