ReviewMedicine2025
Was the occurrence of mycoplasma pneumoniae pneumonia combined with cerebral watershed infarction a coincidence?: A CARE compliant case series and literature review.
Review in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Pentasystem embolism associated with transient antiphospholipid antibodies in severe M.Frontiers in immunology · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
rationaleMycoplasma pneumoniae (MP) is one of the most common respiratory pathogens in children. The prevalence of MP-induced pneumonia (MPP) has increased significantly in China since the outbreak of pediatric respiratory diseases in 2023. MP can affect almost every organ system in the body. The incidence of cerebral infarction in MPP is relatively rare, and the mechanisms involved in the occurrence of MPP with cerebral infarction are not completely clear. PATIENT CONCERNS: The clinical data of children with MPP admitted to Hebei Children's Hospital between January 2018 and January 2024 who developed cerebral infarction during the acute stage were reviewed. Cerebral magnetic resonance imaging revealed cerebral watershed infarction in all 4 children included in the study. The thrombi were detected in other arteries in Cases 1 and case 4, and both of them tested positive for MP-PCR in their cerebrospinal fluid. Cases 2 and case 3 underwent fibrebronchoscopy under basic anesthesia and developed hemiplegia 2 hours and 1 day postoperatively, respectively. DIAGNOSES: Based on the clinical manifestations and laboratory test results, 4 patients could be diagnosed with MPP. These children exhibited positive neurological symptoms during the acute stage of pneumonia, considering the characteristics of the brain magnetic resonance imaging, cerebral watershed infarction can be diagnosed simultaneously.
interventionsPatient 1 and 3 received urokinase thrombolytic therapy, and was also treated with heparin sodium and aspirin for anticoagulation. Patient 2 used a combination of heparin calcium and aspirin to achieve the anticoagulant effect. Patient 4 was treated with calcium heparin for anticoagulation. OUTCOMES: Patient 1 and Patient 4 returned to the baseline level 1 week after the onset of the disease, while Patient 2 and Patient 3 recovered to a roughly normal state within 1 to 2 months after the onset. LESSONS: Focal vasculitis, hypercoagulability and hypoperfusion may be the dominant causes of cerebral watershed infarction in patients with MP infection.
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Registered trials
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