Evidence map›Paper›PMID 41398784›Full record

Observational studyMedicine2025

Exploring the impact of auricular acupressure and nutritional assistance, enhanced with ferulic acid supplementation, on pediatric cough variant asthma: An observational study.

Lu Ye, Yan-Fang Guo, Jin Zhou, Ying-Ying Mi, Jie Zhao, Xiao-Wen Cao

Abstract readObservational Study
In one paragraph

Observational study in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lu YeDepartment of TCM, Gongli Hospital of Shanghai Pudong New Area, Shanghai, China.ORCID 0009-0008-4000-2656
Yan-Fang GuoDepartment of Pediatrics, Gongli Hospital of Shanghai Pudong New Area, Shanghai, China.
Jin ZhouDepartment of Pediatrics, Gongli Hospital of Shanghai Pudong New Area, Shanghai, China.
Ying-Ying MiDepartment of Pediatrics, Gongli Hospital of Shanghai Pudong New Area, Shanghai, China.
Jie ZhaoDepartment of TCM, Gongli Hospital of Shanghai Pudong New Area, Shanghai, China.
Xiao-Wen CaoDepartment of TCM, Gongli Hospital of Shanghai Pudong New Area, Shanghai, China.

Funding

Le-yi Du. Key Specialty of Pudong New Area (Pulmonary Disease of TCM) SHGZS-202218Project Leader,Le-yi Du. Key Specialty of Pudong New Area PWRzm2020-07Traditional Chinese Medicine Research Project of Shanghai Municipal Health Commission 2020LP046
6 · The paper itself

Abstract

Cough variant asthma (CVA) is a common cause of chronic cough in children and significantly affects their health and quality-of-life. To explore potential complementary treatment strategies, we conducted a retrospective observational study evaluating the clinical outcomes of auricular acupressure combined with nutritional assistance supplemented with ferulic acid in pediatric CVA. Medical records of 236 children diagnosed with CVA and treated at the Department of Traditional Chinese Medicine, Gongli Hospital of Shanghai Pudong, between April 2022 and November 2024, were reviewed. Based on treatment received, patients were categorized into a treatment group (auricular acupressure plus ferulic acid supplementation) or a control group (standard care only). Primary outcomes were changes in the Cough Severity Index (CSI), while secondary outcomes included Pediatric Asthma Quality of Life Questionnaire (PAQLQ) scores and pulmonary function tests. At 3, 6, and 12 months, the treatment group showed significantly greater reductions in CSI scores (P < .05) compared with controls. Improvements in lung function indices (FEV1, FVC) were also more pronounced in the treatment group (P < .01). Additionally, quality-of-life scores increased significantly among patients receiving the integrative therapy. These findings suggest that, in this retrospective cohort, the combination of auricular acupressure with ferulic acid supplementation was associated with enhanced symptom relief, lung function, and quality of life in children with CVA. This integrative approach warrants further prospective and randomized investigations to validate its clinical value.

Indexed as

AcupressureAsthmaCoughCoumaric AcidsChildChild, PreschoolCombined Modality TherapyCough-Variant AsthmaDietary SupplementsFemaleHumansMaleQuality of LifeRespiratory Function TestsRetrospective StudiesSeverity of Illness IndexCoumaric Acidsferulic acidauricular acupressureferulic acidlung functionnutritional supplementationpediatric cough variant asthma

Identifiers

PMID41398784
PMCPMC12708130

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.