ArticleBMC pediatrics2025
Physical growth and neurodevelopmental indicators at corrected 6 months of age in preterm infants born at 22-32 weeks gestation: a single-center study.
Article in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveTo investigate the physical growth and neurodevelopmental indicators of Gestational age(GA)< 32 weeks infants at 6 months corrected age.
methodsThis study included 116 infants, retrospectively analyzing GA<32 weeks infants who discharged from Tianjin Central Hospital of Gynecology and Obstetrics between April 2023 and August 2024. General movements (GMs) assessment was performed at 1 month corrected age. Physical Growth Indicators, GMs and Gesell Developmental Diagnosis Scale (GDDS) assessments were conducted at 3 and 6 months corrected age.
resultsThe proportion of abnormal GMs at 3 months corrected age (3.44%) was lower than that at 1 month corrected age (86.21%).At 6 months corrected age, the proportion of infants with a developmental quotient (DQ) ≤ 75 was 43.10%, lower than 69.82% at 3 months corrected age. GA and multiple births were independent risk factors for DQ ≤ 75 at 3 months corrected age. GA, early intervention, and intracranial hemorrhage were independent risk factors for DQ ≤ 75 at 6 months corrected age.
conclusionAt 6 months corrected age, GA<32 weeks infants exhibited greater neurodevelopmental outcome. Standardized follow-up and early neurodevelopmental interventions should be further strengthened for preterm infants to reduce the occurrence of adverse outcomes.
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