Evidence map›Paper›PMID 41398515›Full record

ReviewDocumenta ophthalmologica. Advances in ophthalmology2026

A practical introduction to wavelet analysis in electroretinography.

Yousif J Shwetar, David S Lalush, Alice Y Zhang, J Jason McAnany, Brett G Jeffrey, Melissa A Haendel

Abstract readReview
In one paragraph

Review in Documenta ophthalmologica. Advances in ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Yousif J ShwetarJoint Department of Biomedical Engineering, University of North Carolina and North Carolina State University, Chapel Hill, NC, USA. yousif_shwetar@med.unc.edu.ORCID 0000-0002-0587-4693
David S LalushJoint Department of Biomedical Engineering, University of North Carolina and North Carolina State University, Chapel Hill, NC, USA.ORCID 0000-0002-7240-929X
Alice Y ZhangDepartment of Ophthalmology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID 0000-0001-5194-5256
J Jason McAnanyDepartment of Ophthalmology and Visual Sciences, University of Illinois Chicago, Chicago, IL, USA.ORCID 0000-0003-1192-3487
Brett G JeffreyOphthalmic Genetics and Visual Function Branch, National Eye Institute, NIH, Bethesda, MD, USA.ORCID 0000-0001-9549-0644
Melissa A HaendelDepartment of Genetics, University of North Carolina, Chapel Hill, NC, USA.ORCID 0000-0001-9114-8737

Funding

Improvements to the LinkML framework to support the Phenomics First open science resourceRM1HG010860 · NHGRI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HAENDEL, MELISSA A, MUNGALL, CHRISTOPHER J · 2020 to 2024
$10.3M
Mechanisms of Early Functional Loss in Diabetic Eye DiseaseR01EY026004 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI James JASON McAnany · 2016 to 2026
$4.2M
NEI NIH HHS Intramural Research ProgramNHGRI NIH HHS 7RM1HG010860NHGRI NIH HHS RM1 HG010860NIH HHS R01EY026004University of Illinois at Chicago P30EY001792
6 · The paper itself

Abstract

purposeTo provide a conceptual understanding of the continuous and discrete wavelet transforms (CWT, DWT) for clinical electroretinography (ERG) analysis, and how these methods uncover time-frequency features that complement traditional time-domain analysis.

methodsA technical overview without the use of mathematical formula describing the basics of CWT and DWT and implementation considerations. We also review an example of four standard ISCEV full-field ERG (ffERG) recordings from a healthy 32-year-old male.

resultsWavelet analysis uncovered time-frequency signatures absent in raw traces. In DA 0.01 cd s/m

conclusionsCWT and DWT provide complementary and objective insight into ERG responses. Open-source MATLAB toolkit and step-by-step tutorial provided herein lower technical barriers and enable use by the broader community.

Indexed as

ElectroretinographyRetinaWavelet AnalysisAdultHumansMaleDiagnosticsElectroretinographyFourier transformMetricsSignal processingWavelet transform

Identifiers

PMID41398515
PMCPMC12948838

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.