Evidence map›Paper›PMID 41398372›Full record

ArticleMolecular psychiatry2026

Downregulation of integrin α3 in ADHD mirrored in mutant mouse model by dopamine-dependent hippocampal AMPAR expression.

Xiaojuan Yao, Ruiying Chen, Jingxiang Zhu, Ruiqing Hou, Shitong Xiang, Tianye Jia, Yuelin Gu, Zhenyu Wang, Han Hu, Hongting Chen and 7 more

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Xiaojuan Yao *Department of Anesthesiology, Huashan Hospital; Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence, Ministry of Education; Behavioral and Cognitive Neuroscience Center, Institute of Science and Technology for Brain-Inspired Intelligence, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200433, China.
Ruiying Chen *Department of Anesthesiology, Huashan Hospital; Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence, Ministry of Education; Behavioral and Cognitive Neuroscience Center, Institute of Science and Technology for Brain-Inspired Intelligence, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200433, China.
Jingxiang Zhu *Department of Anesthesiology, Huashan Hospital; Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence, Ministry of Education; Behavioral and Cognitive Neuroscience Center, Institute of Science and Technology for Brain-Inspired Intelligence, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200433, China.ORCID http://orcid.org/0009-0000-0428-4512
Ruiqing HouDepartment of Anesthesiology, Huashan Hospital; Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence, Ministry of Education; Behavioral and Cognitive Neuroscience Center, Institute of Science and Technology for Brain-Inspired Intelligence, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200433, China.
Shitong XiangDepartment of Anesthesiology, Huashan Hospital; Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence, Ministry of Education; Behavioral and Cognitive Neuroscience Center, Institute of Science and Technology for Brain-Inspired Intelligence, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200433, China.ORCID http://orcid.org/0000-0002-5513-4714
Tianye JiaDepartment of Anesthesiology, Huashan Hospital; Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence, Ministry of Education; Behavioral and Cognitive Neuroscience Center, Institute of Science and Technology for Brain-Inspired Intelligence, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200433, China.ORCID http://orcid.org/0000-0001-5399-2953
Yuelin GuDepartment of Anesthesiology, Huashan Hospital; Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence, Ministry of Education; Behavioral and Cognitive Neuroscience Center, Institute of Science and Technology for Brain-Inspired Intelligence, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200433, China.
Zhenyu WangDepartment of Anesthesiology, Huashan Hospital; Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence, Ministry of Education; Behavioral and Cognitive Neuroscience Center, Institute of Science and Technology for Brain-Inspired Intelligence, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200433, China.
Han HuDepartment of Anesthesiology, Huashan Hospital; Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence, Ministry of Education; Behavioral and Cognitive Neuroscience Center, Institute of Science and Technology for Brain-Inspired Intelligence, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200433, China.
Hongting ChenDepartment of Anesthesiology, Huashan Hospital; Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence, Ministry of Education; Behavioral and Cognitive Neuroscience Center, Institute of Science and Technology for Brain-Inspired Intelligence, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200433, China.
He WangDepartment of Anesthesiology, Huashan Hospital; Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence, Ministry of Education; Behavioral and Cognitive Neuroscience Center, Institute of Science and Technology for Brain-Inspired Intelligence, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200433, China.ORCID http://orcid.org/0000-0002-2053-9439
Jianfeng FengDepartment of Anesthesiology, Huashan Hospital; Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence, Ministry of Education; Behavioral and Cognitive Neuroscience Center, Institute of Science and Technology for Brain-Inspired Intelligence, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200433, China.ORCID http://orcid.org/0000-0001-5987-2258
Trevor W RobbinsDepartment of Anesthesiology, Huashan Hospital; Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence, Ministry of Education; Behavioral and Cognitive Neuroscience Center, Institute of Science and Technology for Brain-Inspired Intelligence, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200433, China.ORCID http://orcid.org/0000-0003-0642-5977
Yingwei WangDepartment of Anesthesiology, Huashan Hospital; Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence, Ministry of Education; Behavioral and Cognitive Neuroscience Center, Institute of Science and Technology for Brain-Inspired Intelligence, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200433, China. wangyw@fudan.edu.cn.ORCID http://orcid.org/0000-0003-1633-8834
Michael J HigleyDepartment of Neuroscience, Yale University, New Haven, CT, 06520, USA.ORCID http://orcid.org/0000-0002-5424-6730
Anthony J KoleskeDepartment of Neuroscience, Yale University, New Haven, CT, 06520, USA.ORCID http://orcid.org/0000-0003-4105-9909
Xiao XiaoDepartment of Anesthesiology, Huashan Hospital; Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence, Ministry of Education; Behavioral and Cognitive Neuroscience Center, Institute of Science and Technology for Brain-Inspired Intelligence, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200433, China. xiaoxiao@fudan.edu.cn.ORCID http://orcid.org/0000-0002-4328-0634

Funding

National Natural Science Foundation of China (National Science Foundation of China) 32471083National Natural Science Foundation of China (National Science Foundation of China) 82530042Science and Technology Commission of Shanghai Municipality (Shanghai Municipal Science and Technology Commission) 2018SHZDZX01
6 · The paper itself

Abstract

Integrin α3 is critical for proper neuron-glia cell adhesion and dendrite development, implicated in various neurodevelopmental disorders. In this study, mice deficient in integrin α3 (NEX-Itga3

Indexed as

Attention Deficit Disorder with HyperactivityIntegrin alpha3Receptors, AMPAAnimalsDisease Models, AnimalDopamineDown-RegulationHippocampusMaleMethylphenidateMiceMice, Inbred C57BLMice, KnockoutNeuronsReceptors, Dopamine D1DopamineIntegrin alpha3MethylphenidateReceptors, AMPAReceptors, Dopamine D1

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.