Evidence map›Paper›PMID 41398254›Full record

ArticleBMC musculoskeletal disorders2025

Cross-validation of two independent methods to analyze the sequence of segmental contributions in the cervical spine in extension cineradiographic recordings.

Valérie N E Schuermans, Alexander Breen, Jonathan Branney, Anouk Y J M Smeets, Henk van Santbrink, Toon F M Boselie

Abstract readValidation StudyMulticenter StudyComparative Study
In one paragraph

Article in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

6 authors.

Valérie N E SchuermansDepartment of Neurosurgery, Maastricht University Medical Center, P. Debyelaan 25, Maastricht, 6229 HX, The Netherlands. valerie.schuermans@mumc.nl.
Alexander BreenCollege of Engineering, Mathematics and Physical Sciences, University of Exeter, Exeter, UK.
Jonathan BranneyFaculty of Health and Social Sciences, Bournemouth University, Bournemouth, UK.
Anouk Y J M SmeetsDepartment of Neurosurgery, Maastricht University Medical Center, P. Debyelaan 25, Maastricht, 6229 HX, The Netherlands.
Henk van SantbrinkDepartment of Neurosurgery, Maastricht University Medical Center, P. Debyelaan 25, Maastricht, 6229 HX, The Netherlands.
Toon F M BoselieDepartment of Neurosurgery, Maastricht University Medical Center, P. Debyelaan 25, Maastricht, 6229 HX, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe sequence of segmental contributions (SSC) offers insight into cervical spine motion, yet accurately analyzing these movements remains challenging. This study compares two tracking methods, developed at two independent centers (AECC and MUMC), to establish their agreement and reliability in measuring SSCs across segments C4 to C7. Understanding spinal biomechanics is crucial for future research into cervical spine pathology and dysfunction.

methodsTwelve asymptomatic participants (ages 18-35 for "young" and 55-70 for "elderly") performed flexion-extension movements. MUMC + utilized self-directed motion, while AECC used a guided protocol. To ensure comparability, 26 frames from the second half of each extension movement were analyzed. Agreement was assessed using ICCs, Spearman's Rho, and Bland-Altman analysis. Although the sample size is small, a post-hoc power analysis indicated sufficient power, supported by a high volume of analyzed data points.

findingsHigh intraclass correlation coefficients (ICCs) for the cumulative vertebral rotation (0.97), cumulative intervertebral rotation (0.97) and relative intervertebral rotation (0.93) indicated strong agreement between the two methods. Bland-Altman analysis showed minimal median differences (< 0.2˚) but wider limits of agreement at C6-C7. Normative SSC patterns appeared in 77.8% of younger participants but were absent in elderly participants.

interpretationThis study confirms the reliability of SSC measurement between the two methods, laying the foundation for broader applications. SSC patterns observed in young adults follow a normative pattern, in alignment with previous research. The absence of a fixed pattern in elderly participants could indicate age-related changes or sample variation, warranting cautious interpretation due to the small sample size. Future studies with larger, diverse samples and AI-driven approaches could enhance SSC analysis, enabling better clinical relevance.

Indexed as

Cervical VertebraeRange of Motion, ArticularAdolescentAdultAgedBiomechanical PhenomenaFemaleHumansMaleMiddle AgedReproducibility of ResultsYoung AdultArtificial intelligenceBiomechanicsCervical spineSequence of segmental contributions

Identifiers

PMID41398254
PMCPMC12822052

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