ArticleCardiovascular and interventional radiology2026
Safety and Efficacy of Ticagrelor-Based Dual Antiplatelet Therapy in Endovascular Treatment of Unruptured Intracranial Aneurysms: A Large Single-Center Retrospective Study.
Article in Cardiovascular and interventional radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate the safety and efficacy of ticagrelor-based dual antiplatelet therapy (DUAP) in patients undergoing stent-assisted endovascular treatment (EVT) of unruptured intracranial aneurysms (UIAs) in a large single-center cohort.
methodsWe retrospectively analyzed 153 patients who underwent elective stent-assisted EVT for UIAs and were exclusively managed with aspirin and ticagrelor from January 2021 to December 2024. Clinical outcomes included thromboembolic events (cTE), hemorrhagic events (HE), disability, and mortality. Follow-up involved cone-beam CT for early hemorrhagic complications, scheduled MRI/MR-A, and digital subtraction angiography (DSA) at six months. Outcomes were compared across treatment types: stent-assisted coil embolization (SACE, laser-cut or braided), Y-stenting, flow diversion (FD), and stent monotherapy.
resultsAmong 153 patients (mean age 54.8 ± 13.2 years; 75.2% female), thromboembolic events occurred in 4 (2.6%) and hemorrhagic events in 6 (3.9%) cases during a mean follow-up of 22.5 ± 15.9 months. Permanent disability occurred in 3 patients (2.0%) and mortality in 2 (1.3%). Event rates did not differ significantly among treatment subgroups (p > 0.05).
conclusionTicagrelor-based DUAP was associated with low thromboembolic and hemorrhagic complication rates in patients undergoing stent-assisted endovascular treatment of unruptured intracranial aneurysms, supporting its safety and efficacy in this setting.
Indexed as
Identifiers
41398095What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.