Evidence map›Paper›PMID 41398081›Full record

ReviewNature plants2026

Integrating microbial siderophores into concepts of plant iron nutrition.

Shaohua Gu, Nanqi Wang, Yiran Zheng, Tianqi Wang, Qirong Shen, Fusuo Zhang, Rolf Kümmerli, Zhong Wei, Yuanmei Zuo

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature plants, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Two Cultivars of Peanut (Current issues in molecular biology · 2026
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shaohua Gu *College of Resources and Environmental Sciences, State Key Laboratory of Nutrient Use and Management, National Academy of Agriculture Green Development, China Agricultural University, Beijing, China.ORCID 0000-0003-3071-5747
Nanqi Wang *National Citrus Engineering Research Center, Chongqing Key Laboratory of Citrus, Citrus Research Institute, Southwest University, Chongqing, China.
Yiran ZhengJiangsu Provincial Key Lab for Organic Solid Waste Utilization, Key Lab of Organic-Based Fertilizers of China, Nanjing Agricultural University, Nanjing, China.
Tianqi WangCollege of Resources and Environmental Sciences, State Key Laboratory of Nutrient Use and Management, National Academy of Agriculture Green Development, China Agricultural University, Beijing, China.
Qirong ShenJiangsu Provincial Key Lab for Organic Solid Waste Utilization, Key Lab of Organic-Based Fertilizers of China, Nanjing Agricultural University, Nanjing, China.ORCID 0000-0002-4939-2506
Fusuo ZhangCollege of Resources and Environmental Sciences, State Key Laboratory of Nutrient Use and Management, National Academy of Agriculture Green Development, China Agricultural University, Beijing, China.ORCID 0000-0001-8971-0129
Rolf KümmerliDepartment of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland.ORCID 0000-0003-4084-6679
Zhong WeiJiangsu Provincial Key Lab for Organic Solid Waste Utilization, Key Lab of Organic-Based Fertilizers of China, Nanjing Agricultural University, Nanjing, China. weizhong@njau.edu.cn.ORCID 0000-0002-7967-4897
Yuanmei ZuoCollege of Resources and Environmental Sciences, State Key Laboratory of Nutrient Use and Management, National Academy of Agriculture Green Development, China Agricultural University, Beijing, China. zuoym@cau.edu.cn.ORCID 0000-0001-5128-5788

Funding

National Natural Science Foundation of China (National Science Foundation of China) 32372810National Natural Science Foundation of China (National Science Foundation of China) 32573128National Natural Science Foundation of China (National Science Foundation of China) 42325704National Natural Science Foundation of China (National Science Foundation of China) 42577142Swiss National Science Foundation | National Center of Competence in Research Affective Sciences - Emotions in Individual Behaviour and Social Processes (National Centre of Competence in Research Affective Sciences) 310030_212266
6 · The paper itself

Abstract

Iron is a crucial micronutrient for plants, but its availability in soil is often limited. Iron deficiency compromises plant growth, and low iron content in crops contributes substantially to the 'hidden hunger' that affects human health globally. The elucidation of Strategy I (reduction-based) and Strategy II (phytosiderophore-based) for iron acquisition was a milestone in plant biology and enabled the development of biofortification concepts. However, recent genetic evidence reveals that the boundary between the two strategies is blurred, with many plants possessing elements of both. Here we show that plant iron uptake mechanisms are more complex and diverse than the classical dichotomy suggests. We review evidence for this integrative view and highlight the critical role of microbial siderophores. We explain how plants access iron from microbial siderophores not only indirectly through Strategy I and II pathways but also via the direct uptake of iron-siderophore complexes, an overlooked mechanism that we introduce as Strategy III. We propose three potential routes for this direct uptake and conclude that harnessing Strategy III holds great potential for novel agricultural interventions to enhance iron biofortification and improve human health.

Indexed as

IronPlantsSiderophoresBiofortificationCrops, AgriculturalIronSiderophores

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.