Evidence map›Paper›PMID 41397877›Full record

ArticleRNA (New York, N.Y.)2026

Aub, Vasa, and Armi concentration in phase-separated nuage is dispensable for piRNA biogenesis and transposon silencing.

Samantha Ho, Nicholas P Rice, Tianxiong Yu, Zhiping Weng, William E Theurkauf

Abstract read
In one paragraph

Article in RNA (New York, N.Y.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Samantha Ho *Program in Molecular Medicine, UMass Chan Medical School, Worcester, Massachusetts 01605, USA samantha.ho@umassmed.edu.
Nicholas P Rice *Program in Molecular Medicine, UMass Chan Medical School, Worcester, Massachusetts 01605, USA.
Tianxiong YuProgram in Bioinformatics and Integrative Biology, UMass Chan Medical School, Worcester, Massachusetts 01605, USA.
Zhiping WengProgram in Bioinformatics and Integrative Biology, UMass Chan Medical School, Worcester, Massachusetts 01605, USA.
William E TheurkaufProgram in Molecular Medicine, UMass Chan Medical School, Worcester, Massachusetts 01605, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The piRNA biogenesis machinery localizes to phase-separated nuage granules, but nuage function is not well understood. We therefore assayed nuage composition, piRNA expression, and transposon silencing in

Indexed as

DEAD-box RNA HelicasesDNA Transposable ElementsDrosophila ProteinsGene SilencingPeptide Initiation FactorsRNA-Binding ProteinsRNA, Small InterferingAnimalsCheckpoint Kinase 2DrosophilaDrosophila melanogasterMutationPiwi-Interacting RNARNA Helicasesarmi protein, Drosophilaaub protein, DrosophilaCheckpoint Kinase 2DEAD-box RNA HelicasesDNA Transposable ElementsDrosophila ProteinsPeptide Initiation FactorsPiwi-Interacting RNARNA-Binding ProteinsRNA HelicasesRNA, Small Interferingvas protein, DrosophilaDNA damagegenomic stressnuagepiRNAtransposon

Identifiers

PMID41397877
PMCPMC12908453

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.