Evidence map›Paper›PMID 41397701›Full record

Trial reportObesity (Silver Spring, Md.)2026

The Impact of Baseline Sleep as a Potential Moderator of Weight Loss Intervention in Breast Cancer Survivors: Results From the POWER-Remote Trial.

Jennifer Y Sheng, Ruizhe Chen, Gary L Rosner, Claire F Snyder, Lawrence J Appel, Vered Stearns, Michael T Smith, Janelle W Coughlin

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Obesity (Silver Spring, Md.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01871116 (A Randomized Study Evaluating the Effect of a Remote-Based Weight Loss Program), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01871116 nacompletednot on this map

A Randomized Study Evaluating the Effect of a Remote-Based Weight Loss Program (POWER-remote) on Biomarkers in Women With Early Stage Breast Cancer

TypeinterventionalSponsorSidney Kimmel Comprehensive Cancer Center at Johns HopkinsRan2013 to 2016Enrolled96ConditionsEarly Stage Breast CancerArmsPOWER-remote, Self-directed
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jennifer Y ShengDepartment of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID https://orcid.org/0000-0002-4513-4235
Ruizhe ChenDepartment of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Gary L RosnerDepartment of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Claire F SnyderDepartment of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Lawrence J AppelDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Vered StearnsDepartment of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Michael T SmithDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Janelle W CoughlinDepartment of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Funding

Translational Research Central ServicesP30CA006973 · NCI · JOHNS HOPKINS UNIVERSITY · PI ALAN KEITH MEEKER · 1985 to 2026
$208.6M
Breast Cancer Research FoundationCigarette Restitution Fund at Johns HopkinsNCI NIH HHS P30 CA006973
6 · The paper itself

Abstract

objectiveWe evaluated whether sleep disturbance moderates weight loss in breast cancer survivors. We hypothesized that poor sleep prior to behavioral weight loss (BWL) would be associated with less weight reduction than better sleep.

methodsWomen with prior stage 0-III breast cancer with BMI ≥ 25 kg/m

resultsThere was significant interaction between baseline sleep and treatment (BWL vs. self-directed) for weight loss at 6 (p = 0.024) and 12 months (p = 0.019). Weight loss among better sleepers was -6.16% (SE 1.42%) in BWL versus self-directed arms and -7.53% (SE 2.02%) at 6 (p < 0.001) and 12 months (p = 0.001), respectively. Among poor sleepers, weight loss was -3.15% (SE: 1.58%) and -2.44% (SE: 2.40%) at 6 (p = 0.056) and 12 months (p = 0.321), respectively. BWL had a greater effect among better sleepers but minimal effect among poor sleepers.

conclusionsBWL has greater effects in breast cancer survivors with better versus worse sleep. Studies should evaluate whether sleep disturbance treatment augments weight loss.

trial registrationClinicalTrials.gov identifier NCT01871116.

Indexed as

Breast NeoplasmsCancer SurvivorsObesitySleepSleep Wake DisordersWeight LossAdultAgedBody Mass IndexFemaleHumansMiddle AgedSelf ReportSurvivorsWeight Reduction Programsbreast cancerobesitysleep disturbanceweight loss intervention

Identifiers

PMID41397701
PMCPMC12850570

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.