ArticleThe Journal of international medical research2025
Peri-appendiceal inflammation is associated with appendiceal orifice stenosis and appendiceal body thickening in ulcerative colitis: A case-control study.
Article in The Journal of international medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
ObjectiveThis case-control study aimed to investigate whether peri-appendiceal inflammation is associated with orifice stenosis and appendiceal body thickening in patients with ulcerative colitis.MethodsData from patients with ulcerative colitis-including demographics, symptoms, medications, clinical signs, diagnosis, laboratory tests, colonoscopy findings, and abdominal computed tomography-were recorded and analyzed. Orifice stenosis was defined as apparent narrowing or disappearance of the appendiceal orifice compared with the nearest cecal fold. A thickened appendiceal body was defined as an appendiceal >6 mm with or without surrounding inflammatory changes on computed tomography. The severity of peri-appendiceal inflammation was scored using the Mayo endoscopic score.ResultsA total of 169 patients with ulcerative colitis were included, of whom 17.2% (29/169) had appendiceal orifice stenosis. Appendiceal orifice stenosis was associated with age (odds ratio: 1.042,
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