Evidence map›Paper›PMID 41397128›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Leaf beetles employ tryptophan to detoxify the chemical defenses of poplar trees.

Xingrong Peng, Michael Reichelt, Ana Patricia Baños-Quintana, Beate Rothe, Felix Feistel, Martin Kaltenpoth, Jonathan Gershenzon, Sybille B Unsicker

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Leaf beetles employ tryptophan to detoxify the chemical defenses of poplar trees.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xingrong PengDepartment of Biochemistry, Max Planck Institute for Chemical Ecology, Jena 07745, Germany.ORCID 0000-0002-3100-1888
Michael ReicheltDepartment of Biochemistry, Max Planck Institute for Chemical Ecology, Jena 07745, Germany.ORCID 0000-0002-6691-6500
Ana Patricia Baños-QuintanaDepartment of Biochemistry, Max Planck Institute for Chemical Ecology, Jena 07745, Germany.ORCID 0000-0003-1286-7595
Beate RotheDepartment of Biochemistry, Max Planck Institute for Chemical Ecology, Jena 07745, Germany.
Felix FeistelDepartment of Biochemistry, Max Planck Institute for Chemical Ecology, Jena 07745, Germany.ORCID 0000-0002-7085-4891
Martin KaltenpothDepartment of Insect Symbiosis, Max Planck Institute for Chemical Ecology, Jena 07745, Germany.ORCID 0000-0001-9450-0345
Jonathan GershenzonDepartment of Biochemistry, Max Planck Institute for Chemical Ecology, Jena 07745, Germany.ORCID 0000-0002-1812-1551
Sybille B UnsickerDepartment of Biochemistry, Max Planck Institute for Chemical Ecology, Jena 07745, Germany.

Funding

| Applied Basic Research Foundation of Yunnan Province (Yunnan Province Applied and Basic Research Foundation) 202301AT070332Young Revitalization Talent Support Program "Young Talent" Project XDYC-QNRC-2022-0480
6 · The paper itself

Abstract

Herbivorous insects have evolved many fascinating adaptations to overcome the chemical defenses of their host plants. This study employed targeted and untargeted metabolomics, coupled with isotope labeling, to shed light on the metabolism of salicinoids-potent antiherbivore phenolic defenses present in the Salicaceae family-in the poplar-specialized leaf beetle,

Indexed as

ColeopteraPopulusTryptophanAnimalsBenzyl AlcoholsGastrointestinal MicrobiomeGlucosidesHerbivoryKynurenineMetabolomicsPhenolsPlant LeavesBenzyl AlcoholsGlucosidesKynureninePhenolssalicortinTryptophanChrysomela tremulaedetoxificationPopulus nigrasalicinoidstryptophan

Identifiers

PMID41397128
PMCPMC12745818

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.