ArticleUnited European gastroenterology journal2026
Autologous Adipose Tissue Injection as Treatment for Ileoanal Pouch-Related Fistulae.
Article in United European gastroenterology journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Autologous Adipose Tissue Injection as Treatment for Ileoanal Pouch-Related Fistulae.United European gastroenterology journal · 2026Article
- Is It Stem Cell or Magic Potion? The Case of Autologous Fat Injection.United European gastroenterology journal · 2026Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIleal pouch-anal anastomosis (IPAA) is a standard surgical procedure for ulcerative colitis (UC) and familial adenomatous polyposis. However, pouch-related fistulae (PRF) are a significant complication. There is no consensus on the optimal treatment for PRF.
objectiveThis study evaluated the effectiveness of autologous adipose tissue injection (AATI) as a treatment for PRF.
methodsTwenty-one patients with IPAA and a total of 29 PRF were treated with AATI. Patients who did not achieve healing after the first treatment were offered repeated injections. Patients were followed for a median of 16 months after AATI. Outcomes including clinical healing, treatment complications, and recurrence of PRF were registered.
resultsAfter a single treatment with AATI, 48% of the fistulae were clinically healed. Repeated treatments increased the healing rate to 69%. An additional 14% responded to AATI by reduced secretion from PRF. The procedure was well tolerated with minimal complications.
conclusionAATI appears to be a safe, minimally invasive, and sphincter-saving treatment for PRF with promising healing rates. Further studies with larger cohorts are necessary to validate these findings.
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