Evidence map›Paper›PMID 41396592›Full record

ReviewTranslational vision science & technology2025

Recent Developments in Photoreceptor Optoretinography and Progress Toward Clinical Use.

Siyu Chen, David Huang, Ravi S Jonnal

Abstract readReview
In one paragraph

Review in Translational vision science & technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Siyu ChenCenter for Ophthalmic Optics and Lasers (COOL), Oregon Health Sciences University, Portland, OR, USA.
David HuangCenter for Ophthalmic Optics and Lasers (COOL), Oregon Health Sciences University, Portland, OR, USA.
Ravi S JonnalCenter for Human Ophthalmic Imaging Research (CHOIR), University of California, Davis Eye Center, Sacramento, CA, USA.

Funding

Proteomics CoreP30EY010572 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI John Peter Campbell · 1995 to 2026
$19.4M
OCT-based functional biomarkers for degenerative diseases of the photoreceptor-RPE-choroid neurovascular unitR01EY034340 · NEI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Ravi S. Jonnal, Robert J Zawadzki · 2023 to 2026
$2.2M
Investigating fundamental properties and clinical applications of the optoretinogramR01EY033532 · NEI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Ravi S. Jonnal · 2022 to 2026
$2.0M
Optical Assessment of Photoreceptor Function and IntegrityR01EY036413 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI Siyu Chen · 2025 to 2026
$1.1M
NEI NIH HHS P30 EY010572NEI NIH HHS R01 EY033532NEI NIH HHS R01 EY034340NEI NIH HHS R01 EY036413
6 · The paper itself

Abstract

Optoretinography is an emerging class of methods designed to probe the function of retinal neurons using noninvasive, optical techniques. Early efforts sought to identify sources of functional signal and measure responses using advanced, research-grade imaging systems. In the past few years, some investigators have demonstrated simplified methods for measuring these signals using equipment very similar to what is used in commercial, clinical systems. The goal of this review is to introduce the reader to the sources of the photoreceptor optoretinographic signal and the technologies that have been developed to measure it.

Indexed as

Photoreceptor Cells, VertebrateAnimalsHumans

Identifiers

PMID41396592
PMCPMC12710788

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.