Evidence map›Paper›PMID 41396445›Full record

ArticleSleep & breathing = Schlaf & Atmung2025

Is barbed pharyngoplasty a suitable alternative to CPAP in OSA elderly patients?

Manuele Casale, Antonio Moffa, Peter Baptista, Francesco Iafrati, Iman Al Alfifi, Giannicola Iannella, Rodolfo Lugo, Kenny P Pang, Claudio Vicini

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Article in Sleep & breathing = Schlaf & Atmung, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Manuele CasaleSchool of Medicine, Università Campus Bio-Medico di Roma, Via Álvaro del Portillo, Rome, Italy.
Antonio MoffaSchool of Medicine, Università Campus Bio-Medico di Roma, Via Álvaro del Portillo, Rome, Italy.
Peter BaptistaENT Department, Al Zahra Private Hospital Dubai, Dubai, 23614, United Arab Emirates.
Francesco IafratiUnit of Integrated Therapies in Otolaryngology, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy. Francesco.iafrati@policlinicocampus.it.ORCID http://orcid.org/0000-0001-7944-6707
Iman Al AlfifiUnit of Integrated Therapies in Otolaryngology, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.
Giannicola IannellaDepartment of Organi Di Senso, University Sapienza, Rome, Italy.
Rodolfo LugoDepartment of Otorhinolaryngology, Grupo Medico San Pedro, Monterrey, Mexico.
Kenny P PangAsia Sleep Centre, Singapore, Singapore.
Claudio ViciniDepartment ENT & Audiology, University of Ferrara, Ferrara, 44121, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBarbed Pharyngoplasty (BP), a minimally invasive, muscle-preserving surgical technique utilizing Barbed Sutures (BS) for palatal suspension and remodelling, has shown efficacy in younger cohorts but remains underexplored in older adults. The aim of this study was to show the effectiveness and safety of the BP technique as a standalone surgical treatment in selected elderly patients with moderate-severe OSA and concentric pharyngeal collapse non-compliant, intolerant, or refractory to CPAP.

methodsA retrospective study was conducted on 17 patients aged ≥ 65 years (older group) and 23 patients aged < 65 years (younger group) who underwent BP. Pre- and postoperative assessments included Apnea-Hypopnea Index (AHI), Oxygen Desaturation Index (ODI), Epworth Sleepiness Scale (ESS), and snoring severity via bed partner Visual Analog Scale (VAS).

resultsIn the older group, the mean AHI significantly decreased from 39.9 ± 20.1 to 21.1 ± 14.4 events/hour (p = 0.0002), and ODI from 32.6 ± 21.8 to 17.8 ± 12.5 events/hour (p = 0.002). Postoperative ESS and VAS scores also demonstrated significant improvement (14 ± 6.4 to 6.0 ± 3.2, and 7.9 ± 2.9 to 3.4 ± 1.5, respectively; p < 0.05). Surgical success was achieved in 42% of older group compared to 78% in the younger group. No major complications were observed.

conclusionBP is a viable, safe, and effective surgical option for selected elderly patients with moderate-to-severe OSA who are non-adherent to CPAP therapy are. Although its success rate is lower than in younger populations, likely due to age-related anatomical changes, BP provides clinically significant improvements in respiratory function and symptoms.

Indexed as

Continuous Positive Airway PressurePharynxSleep Apnea, ObstructiveSuture TechniquesAdultAgedAge FactorsFemaleHumansMaleMiddle AgedPolysomnographyRetrospective StudiesBarbed pharyngoplastyBarbed suturesSleep apnea, elderly patients

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.