Evidence map›Paper›PMID 41396438›Full record

ReviewAnalytical and bioanalytical chemistry2026

Analysis and fate of per- and polyfluoroalkyl substances (PFAS) in the global aquatic environment: perspectives and combined risks with microplastics.

Maryam Mallek, Damia Barcelo

Abstract readReview
PubMed Publisher
In one paragraph

Review in Analytical and bioanalytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Maryam MallekLaboratory of Material Sciences and Environment, Faculty of Sciences, University of Sfax, Route de La Soukra Km 3.5, BP 1171, 3000, Sfax, Tunisia.
Damia BarceloChemistry and Physics Department, University of Almeria, Ctra Sacramento S/N, 04120, Almería, Spain. damiab@ual.es.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Per- and polyfluoroalkyl substances (PFAS) are synthetic, highly persistent environmental contaminants increasingly recognized for their global occurrence, bioaccumulation potential, and toxicological impacts. This review provides a critical overview of analytical challenges and the environmental fate of both legacy and emerging PFAS, with particular emphasis on ultrashort-chain compounds such as trifluoroacetic acid (TFA). The existing literature pertaining to PFAS occurrence across aquatic systems, landfill leachates, sewage sludge, and food matrices is synthesized, and their interactions with microplastics (MPs) are examined, underscoring combined risks to ecosystems and human health. Advances in targeted liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) and high-resolution mass spectrometry (HRMS) coupled with non-target analysis (NTA) have greatly expanded PFAS detection, identifying over 750 novel compounds and revealing total concentrations up to seven times higher than targeted screening alone, while gas chromatography-non-target screening (GC-NTS) enables the detection of neutral and volatile PFAS from high-temperature processes. The insights presented aim to support the development of sustainable monitoring, mitigation, and policy frameworks for PFAS management in the context of global water reuse and the circular economy.

Indexed as

Environmental MonitoringFluorocarbonsMicroplasticsWater Pollutants, ChemicalHumansLiquid Chromatography-Mass SpectrometryTandem Mass SpectrometryFluorocarbonsMicroplasticsWater Pollutants, ChemicalHigh-resolution mass spectrometryMicroplasticsNon-target analysisPer- and polyfluoroalkyl substanceTrifluoroacetic acid

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.