ArticleRadiological physics and technology2026
Validation of the count-reduction method for planar bone scintigraphy: a phantom study focused on hot-lesion detection.
Article in Radiological physics and technology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Poisson resampling can be used to synthesize low-count nuclear medicine images from full-count data. However, its fidelity relative to real short acquisitions remains uncertain. Using planar acquisitions of JSP and SIM2 bone phantoms filled with 99mTc, we compared the Poisson-generated and measured images at matched-count reductions (10–90%). The simulated total counts matched the measured counts at all reduction levels. The NMSE increased with a greater count reduction, and the values were similar between the groups at each level. In the bone phantom, the contrast ratio and CNR declined with fewer counts, whereas the %CV increased; the trends and values were similar between the simulated and measured images, even at a 90% reduction rate. These findings indicate that the Poisson-based count reduction can reproduce, without apparent systematic bias, the statistics and image-quality characteristics of true low-count images, supporting the safe and efficient optimization of low-dose and short-time protocols without additional patient scans.
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