Evidence map›Paper›PMID 41396342›Full record

ArticleEJNMMI physics2025

Performance evaluation of the ACTIVE 7 MAX benchtop preclinical PET scanner in accordance with the NEMA NU 4-2008 standard.

Haihao Wang, Kexin Wang, Ziquan Yuan, Chenxi Li, Runze Liao, Yucun Hou, Jianlang Hua, Yi Tang, Qing Ruan, Dejun Han and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EJNMMI physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Haihao Wang *School of Physics and Astronomy, Beijing Normal University, No.19, Xinjiekouwai Street, Haidian District, Beijing, 100875, China.
Kexin Wang *School of Physics and Astronomy, Beijing Normal University, No.19, Xinjiekouwai Street, Haidian District, Beijing, 100875, China.
Ziquan YuanSchool of Physics and Astronomy, Beijing Normal University, No.19, Xinjiekouwai Street, Haidian District, Beijing, 100875, China.
Chenxi LiSchool of Physics and Astronomy, Beijing Normal University, No.19, Xinjiekouwai Street, Haidian District, Beijing, 100875, China.
Runze LiaoSchool of Physics and Astronomy, Beijing Normal University, No.19, Xinjiekouwai Street, Haidian District, Beijing, 100875, China.
Yucun HouSchool of Physics and Astronomy, Beijing Normal University, No.19, Xinjiekouwai Street, Haidian District, Beijing, 100875, China.
Jianlang HuaSchool of Physics and Astronomy, Beijing Normal University, No.19, Xinjiekouwai Street, Haidian District, Beijing, 100875, China.
Yi TangSchool of Physics and Astronomy, Beijing Normal University, No.19, Xinjiekouwai Street, Haidian District, Beijing, 100875, China.
Qing RuanSchool of Physics and Astronomy, Beijing Normal University, No.19, Xinjiekouwai Street, Haidian District, Beijing, 100875, China.
Dejun HanSchool of Physics and Astronomy, Beijing Normal University, No.19, Xinjiekouwai Street, Haidian District, Beijing, 100875, China.
Jianyong JiangSchool of Physics and Astronomy, Beijing Normal University, No.19, Xinjiekouwai Street, Haidian District, Beijing, 100875, China. jianyong@bnu.edu.cn.ORCID http://orcid.org/0000-0001-6482-5915

Funding

Beijing Nova Program 20230484413National Natural Science Foundation of China 12475336
6 · The paper itself

Abstract

introductionACTIVE 7 MAX is a compact benchtop preclinical PET scanner dedicated to high sensitivity and high-resolution imaging of small animals. This study evaluated the performance of the ACTIVE 7 MAX system using the National Electrical Manufacturers Association NU 4-2008 standard protocol.

methodsThe scanner consists of four rings, each containing 14 detector modules. Each detector module is made up of a 16 × 16 array of lutetium yttrium orthosilicate (LYSO) scintillation crystals, with each crystal measuring 1.47 × 1.47 × 10.0 mm

resultsThe average energy resolution for the 56 detector modules in the system was found to be 11.46% in Full Width at Half Maximum (FWHM). The filtered back-projection (FBP) image spatial resolution of a point source varied from 1.57 to 1.81 mm in the radial direction and from 1.58 to 1.71 mm in the tangential direction within the radius of 25 mm. For the Derenzo phantom imaging, the hot rod with a diameter of 1.25 mm was identified. With an energy window of 350-650 keV, the sensitivity at the center of the scanner was 4.18%. The peak noise equivalent count rate (NECR) of 103 kcps was achieved at 22 MBq, and the scatter fraction (SF) is 12%. The reconstructed images of the NEMA image quality phantom show a uniformity of 5.0%, and recovery coefficients for rods with diameters of 1 mm and 5 mm ranging from 0.14 to 0.93. The spillover rates for air-filled and water-filled cold regions were 0.08 and 0.03, respectively.

conclusionThis study evaluated the performance of the ACTIVE 7 MAX preclinical PET system. The results demonstrated excellent imaging performance for molecular imaging in biomedical studies.

Indexed as

InstrumentationPerformance evaluationPETSmall-animal imaging

Identifiers

PMID41396342
PMCPMC12819902

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.