Evidence map›Paper›PMID 41396306›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2026

Ultrasound versus angiographic guided access in transfemoral TAVI: intra-operator evaluation of vascular and bleeding complications.

Niklas Lankisch, Gianmarco Iannopollo, Oliver Dumpies, Ahmed Abdelhafez, Johannes Rotta Detto Loria, Ines Richter, Hans-Josef Feistritzer, Steffen Desch, Thilo Noack, Holger Thiele and 2 more

Abstract readComparative Study
In one paragraph

Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Niklas LankischDepartment of Internal Medicine/Cardiology and Department of Structural Heart Disease/Cardiology, Heart Center Leipzig at Leipzig University, Strümpellstr. 39, 04289, Leipzig, Germany.
Gianmarco IannopolloDepartment of Internal Medicine/Cardiology and Department of Structural Heart Disease/Cardiology, Heart Center Leipzig at Leipzig University, Strümpellstr. 39, 04289, Leipzig, Germany.
Oliver DumpiesDepartment of Internal Medicine/Cardiology and Department of Structural Heart Disease/Cardiology, Heart Center Leipzig at Leipzig University, Strümpellstr. 39, 04289, Leipzig, Germany.
Ahmed AbdelhafezDepartment of Internal Medicine/Cardiology and Department of Structural Heart Disease/Cardiology, Heart Center Leipzig at Leipzig University, Strümpellstr. 39, 04289, Leipzig, Germany.
Johannes Rotta Detto LoriaDepartment of Internal Medicine/Cardiology and Department of Structural Heart Disease/Cardiology, Heart Center Leipzig at Leipzig University, Strümpellstr. 39, 04289, Leipzig, Germany.
Ines RichterDepartment of Internal Medicine/Cardiology and Department of Structural Heart Disease/Cardiology, Heart Center Leipzig at Leipzig University, Strümpellstr. 39, 04289, Leipzig, Germany.
Hans-Josef FeistritzerDepartment of Internal Medicine/Cardiology and Department of Structural Heart Disease/Cardiology, Heart Center Leipzig at Leipzig University, Strümpellstr. 39, 04289, Leipzig, Germany.
Steffen DeschDepartment of Internal Medicine/Cardiology and Department of Structural Heart Disease/Cardiology, Heart Center Leipzig at Leipzig University, Strümpellstr. 39, 04289, Leipzig, Germany.
Thilo NoackDepartment of Structural Heart Disease/Cardiac Surgery, Heart Center Leipzig at Leipzig University, Leipzig, Germany.
Holger ThieleDepartment of Internal Medicine/Cardiology and Department of Structural Heart Disease/Cardiology, Heart Center Leipzig at Leipzig University, Strümpellstr. 39, 04289, Leipzig, Germany.
Nicolas MajunkeDepartment of Internal Medicine/Cardiology and Department of Structural Heart Disease/Cardiology, Heart Center Leipzig at Leipzig University, Strümpellstr. 39, 04289, Leipzig, Germany.
Mohamed Abdel-WahabDepartment of Internal Medicine/Cardiology and Department of Structural Heart Disease/Cardiology, Heart Center Leipzig at Leipzig University, Strümpellstr. 39, 04289, Leipzig, Germany. mohamed.abdel-wahab@medizin.uni-leipzig.de.ORCID http://orcid.org/0000-0002-9596-558X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBoth angiography roadmap (RM) and ultrasound (US) are commonly used to obtain femoral arterial access during transfemoral transcatheter aortic valve implantation (TAVI). In this analysis, we sought to evaluate the effect of implementation of an US-guided approach on vascular and bleeding complications.

methodsVascular complications and bleeding at the main access site were compared using 4-year data from two experienced TAVI-operators, who changed their practice from an exclusively RM- to an exclusively US-guided technique for access in transfemoral TAVI.

resultsA total of 1026 patients were analyzed (RM: n = 485, US: n = 541) with a mean age of 80.7 ± 6.3 years; 47.7% were female and 37.1% received a balloon-expandable valve. Main access vascular complications, bleedings, or their composite were lower in the US-group (RM vs. US: 16.1% vs. 8.3%, p < 0.001). US was a protective factor for vascular complications, bleeding and their composite (adjusted odds ratio [OR] 0.51, 95%-confidence interval [CI] 0.33-0.77, p = 0.002; adjusted OR 0.46, 95%-CI 0.28-0.78, p = 0.003; and adjusted OR: 0.47; 95% CI 0.32-0.70, p < 0.001, respectively). Fluoroscopy time (14 [interquartile range (IQR) 11 - 20] min vs. 13 [IQR 10 - 17] min, p < 0.001), contrast use (88 [IQR 69 - 111] ml vs. 84 [IQR 65 - 110] ml, p = 0.049) and procedure time (52 [IQR 44 - 67] min vs. 49 [IQR 41 - 62] min, p = 0.02) were lower in the US-group.

conclusionsUS-guided femoral access was associated with significantly fewer complications compared with RM-guidance, supporting its adoption even among operators experienced with angiographic guidance.

Indexed as

AngiographyAortic Valve StenosisCatheterization, PeripheralFemoral ArteryHemorrhageTranscatheter Aortic Valve ReplacementUltrasonography, InterventionalAgedAged, 80 and overFemaleHumansMaleRetrospective StudiesRisk FactorsTreatment OutcomeAngiographyRoadmapTAVIUltrasoundVascular access

Identifiers

PMID41396306
PMCPMC13249720

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.