ReviewChemical senses2025
Bitter taste receptors.
Review in Chemical senses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- Bitter 2,5-Diketopiperazines From Cocoa Activate Human Bitter Taste Receptors.Molecular nutrition & food research · 2026Article
- Regulation of the murine preadipocytes differentiation by bitter taste receptor Tas2r108 and Tas2r126.Molecular and cellular biochemistry · 2026Article
- In praise of the hyperbola.Journal of the experimental analysis of behavior · 2026Review
- Pre-treatment with creatinine alters the perceived bitterness-sweetness balance of L-histidine in young Japanese female participants.Chemical senses · 2026Article
- Contribution of Vicine, Convicine, and New Derivatives to the Bitter Off-Taste of Fava Bean Proteins.Journal of agricultural and food chemistry · 2026Article
- New Insight Into Male Infertility: Deviation From Basic Tenets of Life.Oxidative medicine and cellular longevity · 2026Review
- Cell surface localization of receptors considered nonfunctional and orphan bitter taste receptors.Current research in food science · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Hundreds of bitter substances, synthetic or natural, toxic or health beneficial, chemically complex organic molecules or simple inorganic metal salts, surround us and other vertebrates. Their detection is mediated by bitter taste receptors present in the oral cavity and beyond. The present review article summarizes the current knowledge about these highly versatile receptors in humans and other vertebrates. Following the introductory description of taste anatomy and canonical taste signal transduction, a brief section about bitter compounds provides a flavor of their chemical diversity. The main part of the article is devoted to the human bitter taste receptors, their agonist profiles, structures, and sensitivities. For comparison, a section of bitter taste receptors in other species is added, and, to highlight the functional complexity of these molecules, nongustatory bitter taste receptors and their functions are described.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.