Evidence map›Paper›PMID 41395838›Full record

ArticleJournal of applied clinical medical physics2025

Impact of acquisition and reconstruction parameters on quantitative accuracy in dual-layer spectral CT: A phantom study.

Lingxuan Leng, Qizhen Zhu, HuiYing Qu, Bing Zhou, Wenbo Li, Fuquan Zhang, Bo Yang, Jie Qiu

Abstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lingxuan LengDepartment of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.ORCID https://orcid.org/0009-0002-6749-4909
Qizhen ZhuDepartment of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
HuiYing QuDepartment of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Bing ZhouDepartment of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Wenbo LiDepartment of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Fuquan ZhangDepartment of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Bo YangDepartment of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Jie QiuDepartment of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Funding

Ministry of Science and Technology of the People's Republic of China 2022YFC2404606Ministry of Science and Technology of the People's Republic of China 2023YFF0613504National Key R&D Program of China
6 · The paper itself

Abstract

purposeThis study aims to systematically evaluate the impact of different CT acquisition and reconstruction parameters on the accuracy of dual-layer spectral CT-based functional imaging, including effective atomic number (Z

methodsA standardized phantom equipped with various material inserts, including air, soft-tissue-equivalent, polymer, and bone-equivalent materials, was scanned using a dual-layer spectral CT system. The investigated acquisition and reconstruction parameters included tube voltage, tube current-time product (mAs), reconstruction thickness, pitch, and reconstruction filter. Quantitative accuracy was assessed for RED and Z

resultsAcross all acquisition and reconstruction parameters, RED and Z

conclusionDual-layer spectral CT demonstrated quantitative accuracy in functional imaging (ED, Z

Indexed as

AlgorithmsImage Processing, Computer-AssistedPhantoms, ImagingRadiographic Image Interpretation, Computer-AssistedRadiotherapy Planning, Computer-AssistedTomography, X-Ray ComputedHumanseffective atomic numberradiation therapy planningrelative electron densityspectral CTvirtual monochromatic images

Identifiers

PMID41395838
PMCPMC12703825

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.