Evidence map›Paper›PMID 41395573›Full record

ArticleInternational cancer conference journal2025

A case of multiple gastric adenocarcinoma of fundic gland type accidentally found by additional gastrectomy following endoscopic submucosal dissection.

Hiroshi Takeno, Hirohisa Okabe, Hidetoshi Nitta, Masahiro Tomita, Asuka Ono, Daisuke Kuroda, Hideyuki Kuroki, Katsuki Haraoka, Toshiro Masuda, Taizo Hibi and 2 more

Abstract read
In one paragraph

Article in International cancer conference journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hiroshi TakenoDepartment of Gastroenterology, Kumamoto Regional Medical Center, 5-16-10 Honjo, Chuo-Ku, Kumamoto, 860-0811 Japan.
Hirohisa OkabeDepartment of Surgery, Kumamoto Regional Medical Center, 5-16-10 Honjo, Chuo-Ku, Kumamoto, 860-0811 Japan.ORCID 0000-0003-3041-7563
Hidetoshi NittaDepartment of Surgery, Kumamoto Regional Medical Center, 5-16-10 Honjo, Chuo-Ku, Kumamoto, 860-0811 Japan.
Masahiro TomitaDepartment of Surgery, Kumamoto Regional Medical Center, 5-16-10 Honjo, Chuo-Ku, Kumamoto, 860-0811 Japan.
Asuka OnoDepartment of Surgery, Kumamoto Regional Medical Center, 5-16-10 Honjo, Chuo-Ku, Kumamoto, 860-0811 Japan.
Daisuke KurodaDepartment of Surgery, Kumamoto Regional Medical Center, 5-16-10 Honjo, Chuo-Ku, Kumamoto, 860-0811 Japan.
Hideyuki KurokiDepartment of Surgery, Kumamoto Regional Medical Center, 5-16-10 Honjo, Chuo-Ku, Kumamoto, 860-0811 Japan.
Katsuki HaraokaDepartment of Gastroenterology, Kumamoto Regional Medical Center, 5-16-10 Honjo, Chuo-Ku, Kumamoto, 860-0811 Japan.
Toshiro MasudaDepartment of Surgery, Kumamoto Regional Medical Center, 5-16-10 Honjo, Chuo-Ku, Kumamoto, 860-0811 Japan.
Taizo HibiDepartment of Pediatric Surgery and Transplantation, Kumamoto University Graduate School of Medical Sciences, 1-1-1 Honjo, Chuo-Ku, Kumamoto, 860-8556 Japan.
Masaaki IwatsukiDepartment of Gastroenterological Surgery, Graduate School of Life Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto, 860-8556 Japan.
Hiroki SugitaDepartment of Surgery, Kumamoto Regional Medical Center, 5-16-10 Honjo, Chuo-Ku, Kumamoto, 860-0811 Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An octogenarian male underwent upper gastrointestinal (UGI) endoscopy for an annual surveillance program, which identified a 12 mm type 0-IIa lesion on the posterior wall of the gastric fornix. An endoscopic biopsy was performed, raising suspicion for malignancy. Subsequent endoscopic submucosal dissection (ESD) was conducted, and the final histopathological diagnosis confirmed fundic gland-type gastric adenocarcinoma. The tumor exhibited submucosal invasion to a depth of 1000 μm. No evidence of vascular invasion or residual malignant cells at the resection margins was observed. The patient decided to undergo additional proximal gastrectomy to rule out lymph node metastasis. Laparoscopic proximal gastrectomy was performed, and histopathological evaluation revealed no residual carcinoma at the ESD scar and no evidence of lymph node involvement. However, ten additional lesions of fundic gland-type gastric adenocarcinoma were identified, two of which demonstrated submucosal invasion. Biannual follow-up with endoscopy and contrast-enhanced computed tomography has been performed postoperatively. The patient has remained free of recurrence for three years.

Indexed as

GastrectomyGastric adenocarcinoma of the fundic glandSubmucosal invasion

Identifiers

PMID41395573
PMCPMC12696264

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.